Author: C. François

0000000000960999

AUTHOR

C. François

Spread of Klebsiella pneumoniae ST395 non-susceptible to carbapenems and resistant to fluoroquinolones in North-Eastern France

Abstract Objectives Fluoroquinolones (FQs) are a potential treatment for infections caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae that are susceptible to these agents. Methods Owing to increasing non-susceptibility to carbapenems among Enterobacteriaceae, in this study FQ resistance mechanisms were characterised in 36 ertapenem-non-susceptible Klebsiella pneumoniae isolated from North-Eastern France in 2012. The population structure was described by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Results Among the 36 isolates, 13 (36%) carried a carbapenemase encoding-gene. Decreased expression of the OmpK35-encoding gene might be…

research product

CCDC 1543288: Experimental Crystal Structure Determination

Related Article: J. Vigier, C. François, S. Pourchet, G. Boni, L. Plasseraud, V. Placet, S. Fontaine, H. Cattey|2017|Acta Crystallogr.,Sect.E:Cryst.Commun.|73|694|doi:10.1107/S2056989017005370

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PEPhysical Sciences and Engineering
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