0000000000975954
AUTHOR
G. Bosco
A 12-month prospective, observational study evaluating the impact of disease-modifying treatment on emotional burden in recently-diagnosed multiple sclerosis patients: The POSIDONIA study.
Abstract Introduction Depression and anxiety are common among patients with multiple sclerosis (MS) and are frequently present at the time of MS diagnosis. Methods POSIDONIA was a 12-month, observational, prospective study conducted in Italy to evaluate the impact of disease-modifying treatment (DMT) on emotional burden in patients with recently-diagnosed MS. The Hospital Anxiety and Depression Scale (HADS), specifically HADS anxiety (HADS-A) and depression (HADS-D) subscale scores, the Short-Form 36 Health Survey (SF-36) and the Impact of Event Scale – Revised (IES-R) were used to measure patient-reported outcomes. The Hamilton Depression Rating Scale (HDRS), HDRS-17, was used as a measure…
Inflammatory mediators and other biomarkers in co-intoxicated patients after hyperbaric oxygen therapy (HBO2)
Objective: The present study was conducted in attempt to identify reliable biomarkers in predicting the severity of neurological injury. Materials and methods: A number of 30 patients with confirmed CO poisoning and a number of 7 healthy control volunteers were involved into the study. All participants received at least 60 minutes of hyperbaric oxygen therapy (HBO2) at 2.5 atmospheres absolute (ATA). Standard blood gas analysis was performed on 10 mL venous blood samples obtained immediately before and after HBO2. Seven biomarkers and carboxyhemoglobin (COHb) levels were measured. Results: Following HBO2, all patients recovered fully and were discharged in stable condition. Significant diff…
Progetto di un impianto geotermico di piccola potenza
Si presenta la metodologia di progetto utilizzata per il dimensionamento di un campo di sonde geotermiche verticali da asservirsi ad un impianto di riscaldamento geotermico a bassa entalpia di una villetta monofamiliare sita lungo la via Aurelia in Roma. Le proprietà termiche del sottosuolo interessato dall'opera sono state caratterizzate a partire da semplici prove di laboratorio ed il calcolo di dimensionamento delle sonde è ispirato ai criteri proposti dalla normativa tedesca per il dimensionamento d’impianti con potenza termica inferiore a 30 kW; quest’ultimo approccio è stato modificato per tenere in conto della “deriva termica” del sottosuolo legata allo sfruttamento stagionale della …