0000000000976250

AUTHOR

Emmanuella Di Scala

Influence du rapport à l’apprendre sur l’évolution des conceptions scientifiques

International audience

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Autoantibody effects on the cardiac recombinant human serotonin 4 receptor, h5-HT4(e)

National audience

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Etude fonctionnelle du récepteur à la sérotonine humain cardiaque de type 4. Effets des sérums de patients atteints de troubles du rythme auriculaire sur l’activité fonctionnelle du récepteur

Rapport de DEA - 25 pages

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Traitements et cancer : systèmes d’informations et représentations d’un jeune public – étude comparative Stafford-Dijon

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Effects of autoantibodies on the cardiac recombinant human serotonin receptor h5 HT4(e)

National audience

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Effet de l’anticorps antipeptidique AC G21V sur l’activité fonctionnelle du récepteur 5-HT4 humain cardiaque

Rapport de Maîtrise- TER- 17 pages

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Réflexion autour des Représentations en question

National audience

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Effects of the polyclonal antibody anti-G21V on the cardiac h-5-HT4(e) receptors expressed in CHO cells depends upon receptor density

National audience

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Implication du récepteur 5-HT4 cardiaque humain dans la fibrillation auriculaire : rôle d’auto-anticorps dirigés contre ce récepteur ?

The human cardiac 5-HT4 receptor was cloned in 1997. It is functional only in atrial myocytes where it is positively coupled via Gs to the adenylate cyclase, activates the cAMP-dependent protein kinase (PKA) and in consequence phosphorylates a variety of intracellular proteins implicated in excitation-contraction coupling. A number of studies suggest a role for the 5-HT4 receptor in the maintenance or elongation of atrial fibrillation. It is now accepted that certain cardiac pathologies involve auto-immune processes. Antibodies directed against the second extracellular loop of a number of cardiac G-protein linked receptors have been found. The human cardiac 5-HT4 receptor could therefore al…

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Scientific culture’s Representations of students

International audience

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Immunological and functional study of human recombinant serotonin 4 receptor, h5-HT4(e).

National audience

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Immunological analyses of the cardiac h5-HT4(e) receptor

National audience

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