0000000000976496

AUTHOR

G. Pajno

showing 4 related works from this author

Safety and tolerability of seasonal ultra-rush, high-dose sublingual-swallow immunotherapy in allergic rhinitis to grass and tree pollens: an observa…

2009

We conducted a large observational study in 193 children and adolescents with allergic rhinitis due to grass or tree pollens to evaluate the safety and tolerability of an ultrarush high-dose sublingual immunotherapy (SLIT) regimen reaching a maintenance dose of 300 index of reactivity within 90 minutes.Children and adolescents aged 5 to 17 years with at least a 1-year medical history of allergic rhinitis with or without mild to moderate asthma due to tree pollens (birch, alder, hazel) or grass pollens (cocksfoot, meadow grass, rye grass, sweet vernal grass, timothy) were recruited. Standardized grass and tree pollen allergen extracts were used for ultrarush titration and subsequent coseason…

MaleAdolescentAdministration SublingualPoaceaeAllergic rhinitisTreesHumansGrasses; Trees; Ultrarush; Sublingual immunotherapy; Children; Safety; Allergic rhinitis; AsthmaGrassesChildChildrenSublingual immunotherapyAntigens Plant; Trees; Immunotherapy; Humans; Asthma; Child; Pollen; Child Preschool; Poaceae; Rhinitis Allergic Seasonal; Seasons; Adolescent; Administration Sublingual; Female; MaleUltrarushRhinitis Allergic SeasonalAntigens PlantAsthmaChild PreschoolPollenFemaleSeasonsImmunotherapySeasonSafetyTreeHuman
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Fatal anaphylaxis in a 15-year-old boy with Down syndrome.

2011

Settore MED/43 - Medicina LegaleDOWN SYNDROMEFATAL ANAPHYLAXISCeftazidime
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Molecular analysis of sequence variants in the Fcepsilon receptor I beta gene and IL-4 gene promoter in Italian atopic families

2004

The genetic variants in the Fcepsilon receptor I beta gene (Glu237Gly) and the T allele of the (C590T) polymorphism of interleukin (IL)-4 gene promoter were reported to be associated with atopy. But the data of the studies in different populations are contrasting with one another.

AdultHypersensitivity ImmediateMalePolymorphism GeneticGenotypeAdolescentReceptors IgEGenetic Variation; Gene Frequency; Polymorphism Genetic; Humans; Child; Receptors IgE; Genotype; Promoter Regions Genetic; Immunoglobulin E; Adult; Interleukin-4; Hypersensitivity Immediate; Middle Aged; Adolescent; Male; Amino Acid Substitution; FemaleGenetic VariationImmunoglobulin EMiddle AgedGene FrequencyAmino Acid SubstitutionFemaleInterleukin-4ChildPromoter Regions GeneticHuman
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Cross-sectional comparison of the characteristics of respiratory allergy in immigrants and Italian children.

2014

Background: Immigrants represent a good epidemiological model to evaluate the relative influence of environmental and inherited factors on the development of allergy. Several studies on allergy in adults have been published, but few data in children are available. We aimed to investigate the differences, between Italian and immigrant children, in clinical characteristics of respiratory allergy. Methods: This was a multicentre cross-sectional study involving children born in Italy from Italian parents and children born either in Italy or abroad from immigrants. Children referred firstly for allergic respiratory disease (rhinitis/asthma), with an ascertained clinical diagnosis and IgE sensiti…

MalePediatricsmedicine.medical_specialtyAllergyAdolescentmedia_common.quotation_subjectImmunologyImmigrationAllergic asthmaEmigrants and ImmigrantsDiseaseEpidemiologyAllergic rhinitimedicineEthnicityRespiratory HypersensitivityImmunology and AllergyHumansGenetic Predisposition to DiseaseChildChildrenmedia_commonAsthmabusiness.industryRespiratory diseaseRespiratory allergyInfantmedicine.diseaseCross-Sectional StudiesItalyClinical diagnosisChild PreschoolPediatrics Perinatology and Child HealthFemalebusinessImmigrantPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
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