6533b855fe1ef96bd12b0579

RESEARCH PRODUCT

Molecular analysis of sequence variants in the Fcepsilon receptor I beta gene and IL-4 gene promoter in Italian atopic families

L RigoliC Di BellaV ProcopioG BarberioI BarberiL CaminitiS BriugliaC SalpietroG. PajnoStefania La Grutta

subject

AdultHypersensitivity ImmediateMalePolymorphism GeneticGenotypeAdolescentReceptors IgEGenetic Variation; Gene Frequency; Polymorphism Genetic; Humans; Child; Receptors IgE; Genotype; Promoter Regions Genetic; Immunoglobulin E; Adult; Interleukin-4; Hypersensitivity Immediate; Middle Aged; Adolescent; Male; Amino Acid Substitution; FemaleGenetic VariationImmunoglobulin EMiddle AgedGene FrequencyAmino Acid SubstitutionFemaleInterleukin-4ChildPromoter Regions GeneticHuman

description

The genetic variants in the Fcepsilon receptor I beta gene (Glu237Gly) and the T allele of the (C590T) polymorphism of interleukin (IL)-4 gene promoter were reported to be associated with atopy. But the data of the studies in different populations are contrasting with one another.

yearjournalcountryeditionlanguage
2004-02-01
http://hdl.handle.net/10447/102898