0000000000981239

AUTHOR

S Masi

showing 3 related works from this author

Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately …

2017

Background The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We aimed to compare the long-term effects of pioglitazone versus sulfonylureas, given in addition to metformin, on cardiovascular events in patients with type 2 diabetes. Methods TOSCA.IT was a multicentre, randomised, pragmatic clinical trial, in which patients aged 50–75 years with type 2 diabetes inadequately controlled with metformin monotherapy (2–3 g per day) were recruited from 57 diabetes clinics in Italy. Patients were randomly assigned (1:1), by permuted blocks randomisation (block size 10), stratified by site and…

MaleDiabetes and Metabolism ipoglycemic drugs cardiovascualr eventSettore MED/09 - Medicina Internaendocrine system diseasesIMPACTpioglitazone versus sulfonylureasEndocrinology Diabetes and MetabolismGLIMEPIRIDEDiabetes cardiovascular events metformin pioglitazone sulphonylureasType 2 diabetes030204 cardiovascular system & hematologyInternal Medicine; Endocrinology Diabetes and Metabolism; Endocrinologylaw.inventionSettore MED/13 - EndocrinologiaGlibenclamide0302 clinical medicineRandomized controlled triallawGLYCEMIC CONTROLGliclazideInternal medicinediabetes and metabolismRISKeducation.field_of_studydiabetesIncidenceInternal medicine; endocrinology diabetes and metabolism; endocrinologyMiddle AgedINSULINMetforminMetforminTreatment OutcomeEditorialsulphonylureasCardiovascular DiseasesCombinationDrug Therapy CombinationFemaleType 2medicine.drugmedicine.medical_specialtyPopulation030209 endocrinology & metabolismAged; Cardiovascular Diseases; Diabetes Mellitus Type 2; Drug Therapy Combination; Female; Humans; Hypoglycemic Agents; Incidence; Male; Metformin; Middle Aged; Pioglitazone; Sulfonylurea Compounds; Thiazolidinediones; Treatment OutcomeCardiovascular events03 medical and health sciencesendocrinologyGLUCOSE-LOWERING DRUGSDrug TherapyInternal medicineDiabetes MellitusmedicineHumansHypoglycemic AgentssulfonylureaseducationTOSCA.ITAgedPioglitazonebusiness.industryMORTALITYnutritional and metabolic diseasesInsulin resistancemedicine.diseaseSurgeryGlimepirideSulfonylurea CompoundsDiabetes Mellitus Type 2Diabetes Mellitus; Pioglitazone; Insulin resistanceThiazolidinedionesbusinessFOLLOW-UPPioglitazone
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Relationships between diuretic related hyperuricemia and cardiovascular events: data from the URRAH (URic acid Right for heArt Health) study.

2021

Objective Although the relationship between hyperuricemia and cardiovascular events has been extensively examined, data on the role of diuretic-related hyperuricemia are still scanty. The present study was designed to collect information on the relationship between diuretic-related hyperuricemia and cardiovascular events. Methods The URic acid Right for heArt Health (URRAH) study is a nationwide, multicentre, observational cohort study involving data on individuals recruited from all the Italy territory under the patronage of the Italian Society of Hypertension with an average follow-up period of 122.3 ± 66.9 months. Patients were classified into four groups according to the diuretic use (y…

Cardiovascular eventMalemedicine.medical_specialtySettore MED/09 - Medicina InternaPhysiologymedicine.medical_treatmentdiureticRenal functionHyperuricemiaCardiovascular eventcardiovascular events; cardiovascular mortality; diuretic; uric acid030204 cardiovascular system & hematology03 medical and health scienceschemistry.chemical_compoundcardiovascular events0302 clinical medicineuric acidRisk Factorscardiovascular mortalityInternal medicineInternal MedicinemedicineHumans030212 general & internal medicineHyperuricemiaDiureticsHeart healthUric acid cardiovascular events diuretics epidemiologycardiovascular events cardiovascular mortality diuretic uric acidbusiness.industrySerum uric acidMiddle Agedmedicine.diseasechemistryHypertensionUric acidDiureticCardiology and Cardiovascular MedicinebusinessCohort study
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The lexicon of community acquis: how to negotiate the non-negotiable

2009

In the context of the activities aimed to improve and develop the integration and cooperation of new Member States together with the states already belonging to the European Community, EU institutions have carried out a number of measures to increase the coherence of the body of common rights and obligations, binding all the Member States of the European Union (community acquis), for a long time. For this reason, the Commission of the European Community began in 2001 a process of consultation and discussion about the way in which problems resulting from the lack of a correspondence between national contract laws (and related terms) belonging to different legal systems should be dealt with a…

EU institutions lexicon community acquis contract law terminology culture-bound legal conceptsSettore L-LIN/12 - Lingua E Traduzione - Lingua Inglese
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