0000000000982322

AUTHOR

K. Andrews Campbell

showing 2 related works from this author

Deep pain thresholds in the distal limbs of healthy human subjects.

2003

Pressure pain thresholds (PPTs) in distal limbs have been under-investigated despite their potential clinical importance. Therefore, we compared PPTs over nail bed, bony prominences, and muscle in distal parts of upper and lower limbs. We investigated 12 healthy subjects using three handheld devices: a spring-loaded, analogue pressure threshold meter (PTM) with two operating ranges, and an electronic Algometer. PPTs were determined with three series of ascending stimulus intensities with a ramp of about 50 kPa/s. PPTs were normally distributed in logarithmic space. PPTs over different tissues varied significantly (ANOVA, p0.001): mean thresholds and 95% confidence intervals were 615 kPa (26…

AdultMalePain ThresholdPressure painStimulus (physiology)Functional LateralityReference ValuesPhysical StimulationPressureMedicineHumansDeep painPeripheral NervesMuscle SkeletalPain MeasurementObserver Variationbusiness.industryFootHealthy subjectsNociceptorsExtremitiesAnatomyMiddle AgedHandConfidence intervalAnesthesiology and Pain MedicineNociceptionFemaleAnalysis of varianceTrunk musclebusinessEuropean journal of pain (London, England)
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Quantitative sensory testing: a comprehensive protocol for clinical trials.

2004

We have compiled a comprehensive QST protocol as part of the German Research Network on Neuropathic Pain (DFNS) using well established tests for nearly all aspects of somatosensation. This protocol encompasses thermal as well as mechanical testing procedures. Our rationale was to test for patterns of sensory loss (small and large nerve fiber functions) or gain (hyperalgesia, allodynia, hyperpathia), and to assess both cutaneous and deep pain sensitivity. The practicality of the QST protocol was tested in 18 healthy subjects, 21-58 years, half of them female. All subjects were tested bilaterally over face, hand and foot. We determined thermal detection and pain thresholds including a test fo…

AdultMalePain Thresholdmedicine.medical_specialtyAudiologyClinical ProtocolsThreshold of painmedicineHumansPain MeasurementClinical Trials as TopicReproducibility of ResultsSensory lossHypoesthesiaMiddle AgedAnesthesiology and Pain MedicineAllodyniaHyperalgesiaResearch DesignAnesthesiaNeuropathic painHyperalgesiaHyperpathiaBody regionFemalemedicine.symptomPsychologyEuropean journal of pain (London, England)
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