0000000000984963
AUTHOR
Karl-erhard Müller
Mass spectrometrical detection of polymer particles in capsule tissue surrounding joint endoprotheses of polyethyleneterephthalate
Pyrolysis mass spectrometry of synthetic high polymers is described. The method is used to detect polymer wear particles in capsule tissue surrounding endoprotheses with polyethyleneterephthalate parts. An approximation of semi-quantitative determination of the polymer wear will be discussed.
Detection of poly(methylmethacrylate) wear particles in capsule tissue surrounding endoprotheses by pyrolysis gas chromatography
Pyrolysis gas chromatography (PGC) is used to detect polymer wear particles in capsule tissue surrounding endoprotheses implanted with poly(methylmethacrylate) as bone cement. The method allows the detection of the polymer incorporated in tissue even in the range of 1 weight%.
Fluorescence labelling of organic acidic compounds with 4-bromomethyl-7-methoxycoumarin (Br-Mmc)
4-Bromomethyl-7-methoxycoumarin (Br-Mmc) is introduced as a fluorescence marker for aromatic and heterocyclic acids. To investigate the applicability of this method on substances of different chemical classes, screening experiments with 110 compounds were carried out using a microrefluxer. Most aromatic and heterocyclic monocarboxylic acids gave Mmc-esters which are fluorescent on thin-layer plates, like the Mmc-esters of fatty acids, which have been previously investigated. Strong acids, alcohols, amides and most amines did not react, whereas certain cyclic amines such as piperidine gave strongly fluorescent derivatives. Mmc-phenyl ethers shows only weak fluorescence. A new standard proced…