0000000000987945
AUTHOR
Stefan Schumacher
showing 2 related works from this author
miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling
2012
The small GTPase RhoG plays a central role in actin remodelling during diverse biological processes such as neurite outgrowth, cell migration, phagocytosis of apoptotic cells, and the invasion of pathogenic bacteria. Although it is known that RhoG stimulates neurite outgrowth in the rat pheochromocytoma PC12 cell line, neither the physiological function nor the regulation of this GTPase in neuronal differentiation is clear. Here, we identify RhoG as an inhibitor of neuronal process complexity, which is regulated by the microRNA miR-124. We find that RhoG inhibits dendritic branching in hippocampal neurons in vitro and in vivo. RhoG also inhibits axonal branching, acting via an ELMO/Dock180/…
Topological edge states of nonequilibrium polaritons in hollow honeycomb arrays
2020
We address topological currents in polariton condensates excited by uniform resonant pumps in finite honeycomb arrays of microcavity pillars with a hole in the center. Such currents arise under combined action of the spin–orbit coupling and Zeeman splitting, which breaks the time-reversal symmetry and opens a topological gap in the spectrum of the structure. The most representative feature of this structure is the presence of two interfaces, inner and outer ones, where the directions of topological currents are opposite. Due to the finite size of the structure, polariton–polariton interactions lead to coupling of the edge states at the inner and outer interfaces, which depends on the size o…