Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…

Safety of hospital discharge before return of bowel function after elective colorectal surgery

Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multiva…

Lung cancer incidence in young women (20-49 years) reached incidence in young men

Il grafico, basato sui dati AIRTUM 1992- 2007,mostra l’andamento dell’incidenza di tumore del polmone nei giovani adulti di età 20-49 anni in entrambi i sessi. I

In 2014 cancer registration covers more than half of the Italian population [Nel 2014 la registrazione dei tumori in Italia è estesa a oltre la metà del Paese]

After the increasing trend in the Nineties, in Italy incidence of tumours in children (0-14 years) is decreasing [Dopo l'aumento registrato negli anni Novanta, in Italia l'incidenza dei tumori infantili (0-14 anni) è in diminuzione]

Global surveillance of trends in cancer survival 2000-14 (concord-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

Eser, Sultan (Balikesir Author)

Safety of primary anastomosis following emergency left sided colorectal resection: an international, multi-centre prospective audit

Introduction: Some evidence suggests that primary anastomosis following left sided colorectal resection in the emergency setting may be safe in selected patients, and confer favourable outcomes to permanent enterostomy. The aim of this study was to compare the major postoperative complication rate in patients undergoing end stoma vs primary anastomosis following emergency left sided colorectal resection. Methods: A pre-planned analysis of the European Society of Coloproctology 2017 audit. Adult patients (> 16 years) who underwent emergency (unplanned, within 24 h of hospital admission) left sided colonic or rectal resection were included. The primary endpoint was the 30-day major complic…

In the last 15 years, survival in Italian children (0-14 years) is increased to 12%. [Negli ultimi 15 anni la sopravvivenza per tumore nei bambini italiani di età 0-14 anni è aumentata del 12%]

Cancer incidence and mortality trends from 2003 to 2014 in Italy.

Objective: To evaluate short-term (2003–2014) cancer incidence and mortality trends in Italy. Methods: Italian Cancer Registries data, available in the AIRTUM database, from 17 out of 20 regions were used. The number of incident cases and deaths were estimated for those registries and those years with incomplete information. Age-standardized rates, overall and stratified by geographic area, region, sex, cancer site, and major age group, were computed. Time trends were expressed as annual percent change of rates. Results: In Italy, among males, incidence rates for all cancers showed during 2003–2014, a significant decrease (−0.9%/year), with stronger reductions in the northwest (−1.3%/year) …

About 1,400 new cancer diagnosis in Italian children (0-14 years) are attended every year (7,000 in 5 years) [Ogni anno sono previste circa 1.400 nuove diagnosi di tumori maligni nei bambini italiani di età 0-14 anni (7.000 nel quinquennio)]