0000000000996517

AUTHOR

Alessandro Grecucci 6

showing 1 related works from this author

Neurochemical correlates of brain atrophy in fibromyalgia syndrome: a magnetic resonance spectroscopy and cortical thickness study

2020

(1) Background: Recently, a series of clinical neuroimaging studies on fibromyalgia (FM) have shown a reduction in cortical volume and abnormally high glutamate (Glu) and glutamate + glutamine (Glx) levels in regions associated with pain modulation. However, it remains unclear whether the volumetric decreases and increased Glu levels in FM are related each other. We hypothesized that higher Glu levels are related to decreases in cortical thickness (CT) and volume in FM patients. (2) Methods: Twelve females with FM and 12 matched healthy controls participated in a session of combined 3.0 Tesla structural magnetic resonance imaging (MRI) and single-voxel MR spectroscopy focused on the thalami…

In vivo magnetic resonance spectroscopymedicine.medical_specialtybrain MRIArticlelcsh:RC321-57103 medical and health sciences0302 clinical medicineNeurochemicalAtrophyNeuroimagingGyrusFibromyalgiaInternal medicinemedicinecortical thicknelcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biology0303 health sciencesbusiness.industryGeneral NeuroscienceMR spectroscopyGlutamate receptorSettore MED/37 - Neuroradiologiacortical thicknessmedicine.diseaseSubcortical gray matterEndocrinologymedicine.anatomical_structurefibromyalgia; glutamate excitotoxicity; cortical thickness; brain MRI; chronic pain; MR spectroscopyMR spectroscopy; brain MRI; chronic pain; cortical thickness; fibromyalgia; glutamate excitotoxicity.fibromyalgiaSettore MED/36 - Diagnostica Per Immagini E Radioterapiabusinesschronic pain030217 neurology & neurosurgeryglutamate excitotoxicity
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