0000000001001041

AUTHOR

Fumiko Maeda

showing 2 related works from this author

Inter- and intra-individual variability of paired-pulse curves with transcranial magnetic stimulation (TMS).

2002

Objectives: Previous studies have evaluated the variability of motor thresholds (MTs) and amplitude of motor-evoked potentials (MEPs) to transcranial magnetic stimulation (TMS) within and across individuals. Here we evaluate the reproducibility and inter-hemispheric variability of measures of cortical excitability using the 'conventional' paired-pulse (PP) TMS technique. Methods: We studied PP curves of the left and right hemisphere in 10 healthy subjects on two separate days 2 weeks apart. The inter-stimulus intervals studied were 1, 3, 6, 8, 10 and 12 ms with the conditioning stimulus being 80% of the resting MT, and a single test stimulus producing MEPs of approximately 0.8 mV peak-to-pe…

AdultMalemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentNeurophysiologyAudiologyStimulus (physiology)Lateralization of brain functionElectromagnetic FieldsPhysiology (medical)medicineHumansHealthy subjectsDominance CerebralObserver VariationReproducibilityMotor CortexMotor controlReproducibility of ResultsCortical excitabilityPaired-pulseNeurophysiologyMiddle AgedEvoked Potentials MotorSensory SystemsElectric StimulationTranscranial magnetic stimulationmedicine.anatomical_structureNeurologySensory ThresholdsLateralityFemaleNeurology (clinical)PsychologyNeuroscienceTranscranial magnetic stimulationMotor cortexClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Modulation of corticospinal excitability by repetitive transcranial magnetic stimulation

2000

Abstract Objective : Repetitive transcranial magnetic stimulation (rTMS) is able to modulate the corticospinal excitability and the effects appear to last beyond the duration of the rTMS itself. Different studies, employing different rTMS parameters, report different modulation of corticospinal excitability ranging from inhibition to facilitation. Intraindividual variability of these effects and their reproducibility are unclear. Methods : We examined the modulatory effects of rTMS to the motor cortex at various frequencies (1, 10, 20 Hz) and at different time-points in twenty healthy volunteers. Results : We observed significant inhibition of MEPs following 1 Hz rTMS and significant facili…

AdultMaleTime Factorsmedicine.medical_treatmentCentral nervous systemPyramidal TractsStimulationbehavioral disciplines and activitiesReference ValuesPhysiology (medical)mental disordersHealthy volunteersmedicineHumansmusculoskeletal neural and ocular physiologyMotor CortexNeurophysiologyEvoked Potentials MotorTranscranial Magnetic StimulationSensory SystemsTranscranial magnetic stimulationElectrophysiologymedicine.anatomical_structurenervous systemNeurologyFacilitationRegression AnalysisFemaleNeurology (clinical)PsychologyNeurosciencepsychological phenomena and processesMotor cortexClinical Neurophysiology
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