0000000001001247

AUTHOR

Lluis Tort

showing 3 related works from this author

Differential expression of the corticosteroid receptors GR1, GR2 and MR in rainbow trout organs with slow release cortisol implants

2012

The present study describes the transcriptional levels of the corticosteroid receptors (CRs) GR1, GR2 and MR in the different organs of the rainbow trout (Oncorhynchus mykiss) in response to a slow release of cortisol, throughout a 10-day period. We show that after short term (1 day after cortisol implantation), when the plasma levels of cortisol emulate an acute stress, the GR2 and MR expression levels were upregulated in the brain and head kidney tissues. This result reflects the role of these organs as regulators of the stress response. In general, the rest of the organs, especially gills, intestine, liver, muscle and spleen, showed decreased transcriptional levels of GR1, GR2 and MR, al…

Blood GlucoseFish Proteinsendocrine systemmedicine.medical_specialtyHydrocortisoneTranscription GeneticPhysiologymedicine.drug_classSpleenBiologyHematocritCarbohydrate metabolismBiochemistryReceptors GlucocorticoidDownregulation and upregulationStress PhysiologicalInternal medicinemedicineAnimalsChronic stressLactic AcidReceptorMolecular BiologyDrug Implantsmedicine.diagnostic_testOxygen transportBrainHead KidneyUp-RegulationReceptors Mineralocorticoidmedicine.anatomical_structureEndocrinologyOrgan SpecificityOncorhynchus mykissCorticosteroidhormones hormone substitutes and hormone antagonistsComparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
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Adaptation to host inVibrio vulnificus, a zoonotic pathogen that causes septicemia in fish and humans

2019

Vibrio vulnificus is a siderophilic pathogen spreading due to global warming. The zoonotic strains constitute a clonal-complex related to fish farms that are distributed worldwide. In this study, we applied a transcriptomic and single gene approach and discover that the zoonotic strains bypassed the iron requirement of the species thanks to the acquisition of two iron-regulated outer membrane proteins (IROMPs) involved in resistance to fish innate immunity. Both proteins have been acquired by horizontal gene transfer and are contributing to the successful spreading of this clonal-complex. We have also discovered that the zoonotic strains express a virulent phenotype in the blood of its main…

Gene Transfer HorizontalAcclimatizationIronFish farmingVirulenceContext (language use)Vibrio vulnificusMicrobiologyMicrobiologyFish Diseases03 medical and health sciencesSepsisZoonosesAnimalsHumansVibrio vulnificusPathogenPhylogenyEcology Evolution Behavior and Systematics030304 developmental biology0303 health sciencesInnate immune systembiology030306 microbiologyFishesbiology.organism_classificationImmunity InnateVibrio InfectionsHorizontal gene transferAdaptationEnvironmental Microbiology
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European Sea Bass (Dicentrarchus labrax) immune status and disease resistance are impaired by arginine dietary supplementation

2015

Infectious diseases and fish feeds management are probably the major expenses in the aquaculture business. Hence, it is a priority to define sustainable strategies which simultaneously avoid therapeutic procedures and reinforce fish immunity. Currently, one preferred approach is the use of immunostimulants which can be supplemented to the fish diets. Arginine is a versatile amino acid with important mechanisms closely related to the immune response. Aiming at finding out how arginine affects the innate immune status or improve disease resistance of European seabass (Dicentrarchus labrax) against vibriosis, fish were fed two arginine-supplemented diets (1% and 2% arginine supplementation). A…

Vibrio anguillarumArginineGlutaminelcsh:MedicineInduced inflammatory responseIn-vitroAquacultureSuperoxidesGrowth-performancelcsh:ScienceDisease ResistanceMultidisciplinarybiologyGeneral MedicinePolymerase chain reactionArginaseGeneral Agricultural and Biological SciencesResearch ArticleRespiratory burstAeromonas-SalmonicidaNitric OxideArginineGeneral Biochemistry Genetics and Molecular BiologyImmune systemImmunityAnimals14. Life underwaterSea bassImmune responseInnate immune systemArginasebusiness.industryInterleukinslcsh:Rbiology.organism_classificationImmunity HumoralDietJuvenile jianFishGene Expression RegulationVibrio InfectionsImmunologyDietary SupplementsBasslcsh:QGene expressionbusinessCarpio Var. JianAmino-acidsSpleenVibrio-Anguillarum
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