0000000001001537

AUTHOR

D. Watson

showing 4 related works from this author

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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The rapid atmospheric monitoring system of the Pierre Auger Observatory

2012

The Pierre Auger Observatory is a facility built to detect air showers produced by cosmic rays above 1017 eV. During clear nights with a low illuminated moon fraction, the UV fluorescence light produced by air showers is recorded by optical telescopes at the Observatory. To correct the observations for variations in atmospheric conditions, atmospheric monitoring is performed at regular intervals ranging from several minutes (for cloud identification) to several hours (for aerosol conditions) to several days (for vertical profiles of temperature, pressure, and humidity). In 2009, the monitoring program was upgraded to allow for additional targeted measurements of atmospheric conditions shor…

[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]AstronomyFOS: Physical sciencesCosmic rayReal-time monitoring01 natural sciencesLarge detector systems for particle and astroparticle physics Real-time monitoring Control and monitor systems onlineOptical telescopeObservatory0103 physical sciencesSHOWERSLarge detector systems for particle and astroparticle physics; Real-time monitoring; Control and monitor systems onlineFLUORESCENCE010303 astronomy & astrophysicsInstrumentationInstrumentation and Methods for Astrophysics (astro-ph.IM)DETECTORMathematical PhysicsRemote sensingEvent reconstructionPierre Auger ObservatoryHigh Energy Astrophysical Phenomena (astro-ph.HE)010308 nuclear & particles physicsLarge detector systems for particle and astroparticle physicsControl and monitor systems online[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]FísicaENERGY-SPECTRUMMonitoring programControl and monitor systems online; Large detector systems for particle and astroparticle physics; Real-time monitoringAerosolATMOSFERA (MONITORAMENTO)Air showerExperimental High Energy PhysicsFísica nuclearAstrophysics - Instrumentation and Methods for AstrophysicsAstrophysics - High Energy Astrophysical Phenomena
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Metabolism of 3-hydroxychrysene by rat liver microsomal preparations

1990

3-Hydroxychrysene, a metabolite of the polycyclic aromatic hydrocarbon (PAH) chrysene, was metabolised by rat liver microsomal preparations obtained from Arochlor 1254-pretreated rats. Eight major metabolites were isolated by high performance liquid chromatography and characterised by u.v. spectroscopy and a variety of mass spectrometric techniques. The metabolites were unambiguously identified as 9-hydroxy-trans-1,2-dihydroxy-1,2-dihydrochrysene and 9-hydroxy-r-1,t-2,t-3,c-4-tetrahydroxy-1,2,3,4-tetrahydrochrysene and tentatively identified as 3-hydroxy-trans-5,6-dihydroxy-5,6-dihydrochrysene (since chrysene is a symmetrical molecule the 3- and 9-positions are equivalent), 9-hydroxy-trans-…

MaleChryseneMetabolitePolycyclic aromatic hydrocarbonToxicologyHigh-performance liquid chromatographyChrysenesGas Chromatography-Mass SpectrometryMass Spectrometrychemistry.chemical_compoundAnimalsPhenolTCPOBiotransformationChromatography High Pressure Liquidchemistry.chemical_classificationChromatographyMolecular StructureRats Inbred StrainsGeneral MedicineMetabolismPhenanthrenesRatschemistryMicrosomes LiverMicrosomeSpectrophotometry UltravioletChemico-Biological Interactions
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ORIGIN: metal creation and evolution from the cosmic dawn

2012

Herder, Jan-Willem den et al.

HOT INTERGALACTIC MEDIUMUNIVERSEChemical evolutionMission7. Clean energy01 natural sciencesSpectral lineSettore FIS/05 - Astronomia E Astrofisica010303 astronomy & astrophysicsmedia_commonPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)NUCLEOSYNTHESISCOSMIC cancer databaseClusters of galaxiesSatellite MissionEpoch (reference date)Astrophysics::Instrumentation and Methods for AstrophysicsFORESTGALAXIESGamma-ray burstsAstrophysics - Instrumentation and Methods for AstrophysicsAstrophysics - High Energy Astrophysical PhenomenaX-ray Mission Gamma-ray bursts Clusters of galaxies Warm-hot intergalactic medium Chemical evolutionWarm-hot intergalactic mediumAstrophysics - Cosmology and Nongalactic AstrophysicsAstrophysics and AstronomyStructure formationCosmology and Nongalactic Astrophysics (astro-ph.CO)Clusters of galaxiemedia_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaREDSHIFTFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic AstrophysicsX-ray Mission Gamma-ray bursts Clusters of galaxies Warm-hot intergalactic medium Chemical evolutionABSORPTION-SPECTRA010309 opticsX-rayYIELDS0103 physical sciencesGamma-ray burstInstrumentation and Methods for Astrophysics (astro-ph.IM)X-ray; Mission; Gamma-ray bursts; Clusters of galaxies; Warm-hot intergalactic medium; Chemical evolutionAstronomyAstronomy and AstrophysicsRedshiftGalaxyUniverse13. Climate actionChemical evolution; Clusters of galaxies; Gamma-ray bursts; Mission; Warm-hot intergalactic medium; X-ray; Astronomy and Astrophysics; Space and Planetary ScienceSpace and Planetary ScienceGamma-ray burstCLUSTERSExperimental Astronomy
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