0000000001011115
AUTHOR
Mariano Toro Rojas
Oral manifestations of Cowden?s disease : presentation of a clinical case
Cowden?s disease, or multiple hamartoma syndrome, is an autosomal dominant genodermatosis, characterized by the presence of multiple cutaneous hamartomas, oral fibromas and benign acral keratosis. It affects multiple organs (breast, thyroids, stomach, colon), with the strong possibility of malignant neoplasia developing in these organs. We present a case of this rare syndrome, highlighting the presentation of some clinical characteristics that, in suspected cases, can help to establish an early diagnosis of this disease, this being of great importance given the high frequency of tumors in people with this clinical picture.
Hiperplasia epitelial focal: una rara enfermedad en nuestro medio
La hiperplasia epitelial focal es una afección benigna asintomática y de muy baja frecuencia en nuestro medio. Aparece como pápulas en labio inferior principalmente, aunque se pueden localizar en mucosa retrocomisural y lengua y con menos frecuencia en labio superior, encía y paladar. Presentamos un caso clínico de una niña de 9 años, saharaui con lesiones que clínica e histológicamente se corresponden con una hiperplasia epitelial focal. Focal epithelial hyperplasia is a benign, asymptomatic disease, occurring with very low frequency within our population. It appears as papules, principally on the lower lip, although it can also be found on the retro-commissural mucosa and tongue, and less…