0000000001020015
AUTHOR
W Koenig
Design and commissioning of the GSI pion beam
We describe the design of the secondary pion beam-line installed at the SIS 18Tm synchrotron at GSI, Darmstadt, and discuss the commissioning results. The experiments were performed with proton and C-12 primary beams at several energies using beryllium production targets. Pion yields in a momentum range between 0.4 and 2.8 GeV/c were identified, At the highest primary beam energies of 3.5 GeV for proton and 2.0 A GeV for carbon ions, the latter beam produces the highest low-momentum pion yield while at momenta of 1.5 GeV/c the yields are comparable and at 2.8 GeV/c the proton beam is superior. A momentum resolution of around 0.5% is achieved and the time resolution (a) ranges from 100 to 15…
Large-scale gene-centric analysis identifies novel variants for coronary artery disease.
Coronary artery disease (CAD) has a significant genetic contribution that is incompletely characterized. To complement genome-wide association (GWA) studies, we conducted a large and systematic candidate gene study of CAD susceptibility, including analysis of many uncommon and functional variants. We examined 49,094 genetic variants in ∼2,100 genes of cardiovascular relevance, using a customised gene array in 15,596 CAD cases and 34,992 controls (11,202 cases and 30,733 controls of European descent; 4,394 cases and 4,259 controls of South Asian origin). We attempted to replicate putative novel associations in an additional 17,121 CAD cases and 40,473 controls. Potential mechanisms through w…
A scintillator based time-of-flight hodoscope with a new type of emitter follower divider
A high precision, time-of-flight hodoscope has been constructed to analyse the secondary pion beam at GSI, Darmstadt. The hodoscope comprises three scintillator planes with the individual scintillator rods read out by photomultipliers in both ends. A new active base of the emitter follower type has been developed for stabilization of voltages at the last dynodes of the photomultiplier. The time resolution of this system was found to be sigma less than or equal to 150 ps for counting rates up to 2 MHz.