0000000001026631

AUTHOR

Istvan Gebefügi

showing 3 related works from this author

Attachment of chloride anion to sugars: mechanistic investigation and discovery of a new dopant for efficient sugar ionization/detection in mass spec…

2012

International audience; A new method for efficient ionization of sugars in the negative-ion mode of electrospray mass spectrometry is presented. Instead of using strongly hydrophobic dopants such as dichloromethane or chloroform, efficient ionization of sugars has been achieved by using aqueous HCl solution for the first time. This methodology makes it possible to use hydrophilic dopants, which are more appropriate for chromatographic separation techniques with efficient sugar ionization and detection in mass spectrometry. The interaction between chloride anions and monosaccharides (glucose and galactose) was studied by DFT in the gas phase and by implementing the polarizable continuum mode…

AnionsSpectrometry Mass Electrospray Ionization[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionInorganic chemistryAnalytical chemistryCarbohydrates010402 general chemistryMass spectrometry01 natural sciencesChloridePolarizable continuum modelCatalysisMass SpectrometryAnthocyaninschemistry.chemical_compoundChloridesIonizationwine analysismedicineMonosaccharideAnion bindingchemistry.chemical_classificationChloroformAqueous solutionMolecular Structure010401 analytical chemistryOrganic ChemistryMonosaccharidesGeneral Chemistry0104 chemical sciencesanalytical methodschemistrydensity functional calculations[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionmedicine.drugChemistry (Weinheim an der Bergstrasse, Germany)
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The chemodiversity of wines can reveal a metabologeography expression of cooperage oak wood

2009

Wine chemical compositions, which result from a complex interplay between environmental factors, genetic factors, and viticultural practices, have mostly been studied using targeted analyses of selected families of metabolites. Detailed studies have particularly concerned volatile and polyphenolic compounds because of their acknowledged roles in the organoleptic and therapeutic properties. However, we show that an unprecedented chemical diversity of wine composition can be unraveled through a nontargeted approach by ultrahigh-resolution mass spectrometry, which provides an instantaneous image of complex interacting processes, not easily or possibly resolvable into their unambiguous individu…

WineMultidisciplinaryChemistryOrganolepticfood and beveragesWineBiological SciencesWoodMass SpectrometryQuercusMetabolomicsChemical diversityBotanyHumansStatistical analysis
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Expressing forest origins in the chemical composition of cooperage oak woods and corresponding wines by using FTICR-MS.

2008

A non-targeted, ultra-high-resolution mass spectrometric, direct analysis of oak-wood extracts from two species (Quercus robur L. and Quercus petraea Liebl.) from three French forests, and of a wine aged in barrels derived therefrom has been performed to identify families of metabolites that could discriminate both the species and the geographical origin of woods. From 12 T ultra-high-resolution Fourier transform ion cyclotron resonance mass spectra of wood extracts, hundreds of mass signals were identified as possible significant biomarkers of the two species, with phenolic and carbohydrate moieties leading the differentiation between Q. robur and Q. petraea, respectively, as corroborated …

WineMagnetic Resonance SpectroscopybiologyChemistryOrganic ChemistryAnalytical chemistryWineGeneral Chemistrybiology.organism_classificationMass spectrometryMass spectrometricWoodCatalysisFourier transform ion cyclotron resonanceMass SpectrometryQuercus roburQuercusData Interpretation StatisticalBotanyMass spectrumQuercus petraeaChemical compositionChromatography High Pressure LiquidChemistry (Weinheim an der Bergstrasse, Germany)
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