0000000001031016

AUTHOR

Esther Carrera

showing 2 related works from this author

Prevention of Teratogenesis in Pregnancies of Obese Rats by Vitamin E Supplementation

2021

Congenital malformations are a common adverse outcome in pregnancies complicated by pregestational obesity, although the underlying mechanisms are still unrevealed. Our aim was to study the effect of oxidative stress in obesity-induced teratogenesis. Wistar rats were fed a high-fat diet for 13 weeks, with (OE group) or without (O group) vitamin E supplementation. Then, rats were mated and sacrificed at day 11.5 of gestation. Embryos from O dams presented a 25.9 ± 3.5% rate of malformations (vs. 8.7 ± 3.4% in C rats), which was reduced in the OE group (11.5 ± 2.3%). Pregestational obesity induced hepatic protein and DNA oxidation and a decline in antioxidant enzymes. Importantly, glutathione…

0301 basic medicinemedicine.medical_specialtyobesityAntioxidantPhysiologymedicine.medical_treatmentEmbryo malformationClinical Biochemistry030209 endocrinology & metabolismRM1-950vitamin Emedicine.disease_causeBiochemistryArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinemedicineoxidative stressVitamin EButhionine sulfoximineObesityglutathioneMolecular Biologyembryo malformation; teratogenesis; oxidative stress; glutathione; vitamin E; obesitybusiness.industryVitamin EEmbryoCell BiologyGlutathioneDNA oxidationGlutathioneembryo malformation030104 developmental biologyEndocrinologychemistryOxidative stressGestationteratogenesisTeratogenesisTherapeutics. PharmacologybusinessOxidative stress
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Cytological and molecular characterization of three gametoclones of Citrus clementina

2013

Abstract Background Three gametoclonal plants of Citrus clementina Hort. ex Tan., cv. Nules, designated ESP, FRA, and ITA (derived from three labs in Spain, France, and Italy, respectively), were selected for cytological and molecular characterization in order to elucidate genomic rearrangements provoked by haploidization. The study included comparisons of their ploidy, homozygosity, genome integrity, and gene dosage, using chromosome counting, flow cytometry, SSR marker genotyping, and array-Comparative Genomic Hybridization (array-CGH). Results Chromosome counting and flow cytometry revealed that ESP and FRA were haploid, but ITA was tri-haploid. Homozygous patterns, represented by a sing…

0106 biological sciencesCitrus[SDV]Life Sciences [q-bio]ÉvolutionPlant ScienceHaploidyHORT EX TAN01 natural sciencesGenomeF30 - Génétique et amélioration des planteshttp://aims.fao.org/aos/agrovoc/c_3185SSRSMARKERShttp://aims.fao.org/aos/agrovoc/c_2091http://aims.fao.org/aos/agrovoc/c_8837Citrus clementinaGynogénèseGenetics0303 health scienceshttp://aims.fao.org/aos/agrovoc/c_1637Homozygotehttp://aims.fao.org/aos/agrovoc/c_27583http://aims.fao.org/aos/agrovoc/c_26859Culture d'anthèreCytologieRECOVERYSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeGENOMEhttp://aims.fao.org/aos/agrovoc/c_3490[SDE]Environmental SciencesGametoclonal variationhttp://aims.fao.org/aos/agrovoc/c_6ce991ddPloidyhttp://aims.fao.org/aos/agrovoc/c_4026Genome PlantResearch ArticleLocus des caractères quantitatifsSéquence nucléotidiqueAnther cultureGamèteLocus (genetics)BiologyGenome sequencingGene dosageAnther culture Gynogenesis Gametoclonal variation Genome sequencingDNA sequencinghttp://aims.fao.org/aos/agrovoc/c_489103 medical and health sciencesGynogenesisRETICULATA BLANCOREGENERATIONHaploïdiehttp://aims.fao.org/aos/agrovoc/c_3081Anther culture;Gynogenesis;Gametoclonal variation;Genome sequencing;HORT EX TAN;ANTHER CULTURE;RETICULATA BLANCO;REGENERATION;RECOVERY;MARKERS;GENOME;SSRS[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyAllelehttp://aims.fao.org/aos/agrovoc/c_37974GeneGenotypingAlleles030304 developmental biologyhttp://aims.fao.org/aos/agrovoc/c_2745Biologie moléculairehttp://aims.fao.org/aos/agrovoc/c_7273010606 plant biology & botany
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