0000000001034095

AUTHOR

Calogero Stelletta

showing 2 related works from this author

Anomalous water dynamics in brain: a combined diffusion magnetic resonance imaging and neutron scattering investigation

2019

International audience; Water diffusion is an optimal tool for investigating the architecture of brain tissue on which modern medical diagnostic imaging techniques rely. However, intrinsic tissue heterogeneity causes systematic deviations from pure free-water diffusion behaviour. To date, numerous theoretical and empirical approaches have been proposed to explain the non-Gaussian profile of this process. The aim of this work is to shed light on the physics piloting water diffusion in brain tissue at the micrometre-to-atomic scale. Combined diffusion magnetic resonance imaging and first pioneering neutron scattering experiments on bovine brain tissue have been performed in order to probe dif…

Medical diagnosticMaterials science[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/ImagingQuantitative Biology::Tissues and OrgansPhysics::Medical PhysicsBiomedical EngineeringBiophysicsproton dynamicsBioengineeringbrain imagingNeutron scatteringBiochemistryAtomic unitsBiomaterials03 medical and health sciences0302 clinical medicineTissue heterogeneityWater dynamicsNuclear magnetic resonancemedicineAnimalsDiffusion (business)030304 developmental biologydiffusion magnetic resonance imaging0303 health sciencesProton dynamicmedicine.diagnostic_testneutron scatteringBrainWaterMagnetic resonance imagingwater diffusionLife Sciences–Physics interfaceMagnetic Resonance ImagingSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Neutron Diffraction[SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/ImagingBovine brainBrain imaging; Diffusion magnetic resonance imaging; Neutron scattering; Proton dynamics; Water diffusionCattle030217 neurology & neurosurgeryBiotechnology
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Water Dynamics in Neural Tissue

2013

Water dynamics in post-mortem two-years old bovine cerebral right hemisphere has been investigated through Elastic and Quasi-elastic Neutron Scattering. Experimental parameters such as stability in time of the proton dynamics, data reproducibility and changes in the tissues dynamics upon the conservation protocol, cryogenic towards formalin addition, have been carefully investigated. Results are extremely encouraging and comparisons to magnetic resonance imaging findings are discussed.

ReproducibilityMaterials sciencemedicine.diagnostic_testProtonneutron scatteringDynamics (mechanics)proton dynamicsGeneral Physics and AstronomyMagnetic resonance imagingNeutron scatteringNuclear magnetic resonanceWater dynamicsmedicineRight hemispherediffusion magnetic resonance imagingJournal of the Physical Society of Japan
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