0000000001034247

AUTHOR

B. Simone

showing 4 related works from this author

Long-term hepatic safety of lomitapide in homozygous familial hypercholesterolaemia

2023

Introduction: Lomitapide is a microsomal triglyceride transfer protein inhibitor for patients with homozygous familial hypercholesterolaemia. Due to its mechanism of action, potential hepatic effects of lomitapide are of clinical interest. This study aimed to determine the long-term hepatic safety of lomitapide. Methods: Data were aggregated from the pivotal phase 3 and extension phase clinical trial with lomitapide (median 5.1 years; serum total bilirubin, transaminases, cytokeratin-18 [CK-18] and enhanced liver fibrosis [ELF] score, fat-soluble vitamins and essential fatty acids), 8-year data from the Lomitapide Observational Worldwide Evaluation Registry (LOWER) and real-world evidence f…

Settore MED/09 - Medicina Internahepatic steatosisliverLomitapidehepatic biomarkershepatic steatosiSettore BIO/18 - Geneticahepatic biomarkerSettore BIO/14 - Farmacologialiver fibrosis.hepatichepatic; hepatic biomarkers; hepatic steatosis; homozygous familial hypercholesterolaemia; liver; liver fibrosis; lomitapidehomozygous familial hypercholesterolaemialiver fibrosis
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Effectiveness of a remote simulation training in mechanical ventilation among trainees.

2022

Pulmonary and Respiratory Medicinemechanical ventilationPulmonology
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Logistic regression of attitudes and coverage for influenza vaccination among Italian Public Health medical residents

2014

Introduction. A few number of literature specifically addresses vaccination uptake among Public Health Residents (PHRs). Influ- enza vaccine attitudes and risk perceptions of PHRs across Italy were studied, contributing to literature on influenza vaccination uptake predictors, in particular among young physicians. Methods. An online survey was conducted in 25 Schools of Public Health in Italy in 2011-2012. Results were analysed using preva- lence and logistic regression methods. Results. A total of 365 Italian public health residents were included in the study. Vaccination uptake was confirmed by 22.2 and 33.2% of PHRs in 2010-2011 and 2011-2012, respectively. For the 2010-2011 influenza se…

AdultMaleRisk perceptionAttitude of Health PersonnelMedical Residents; Influenza vaccination; Risk perceptionInternship and ResidencySettore MED/42 - Igiene Generale E ApplicataInfluenza vaccinationLogistic ModelsItalyInfluenza VaccinesInfluenza HumanHumansOriginal ArticleMedical ResidentsFemalePublic HealthMedical ResidentJournal of Preventive Medicine and Hygiene
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La Genomica in Sanità Pubblica.
Sintesi delle evidenze e delle conoscenze disponibili sull’utilizzo della genomica ai fini della prevenzione.

2012

Genomica di Sanità Pubblica; test genetici; test genomici; prevenzione; Public Healthtest genomiciprevenzioneGenomica di Sanità PubblicaPublic Healthtest geneticiSettore MED/42 - Igiene Generale E Applicata
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