0000000001034571

AUTHOR

Alfredo Perales-puchalt

0000-0003-4904-5050

showing 2 related works from this author

The negative predictive value of cervical interleukin-6 for the risk assessment of preterm birth.

2013

To determine the potential clinical use of cervical interleukin-6 (IL-6) as a negative predictor of preterm birth in symptomatic women.Observational prospective study carried out in a tertiary hospital.We studied 100 singleton pregnant women with threatened preterm delivery and intact membranes, between 24 and 34 weeks, recruited during the period 2006-2008. A cervical swab for IL-6 detection was taken and a transvaginal ultrasound scan was performed for measuring the cervical length.Five women delivered within 2 d and six women within 7 d. A high cervical IL-6 concentration was found in these women. The area under the ROC curve for cervical IL-6 was 0.97 for deliveries within 2 d after the…

Adultmedicine.medical_specialtyPregnancy Trimester ThirdRisk AssessmentYoung AdultPredictive Value of TestsPregnancymedicinePrevalenceHumansFalse Positive ReactionsProspective cohort studyPreterm deliveryGynecologyTransvaginal ultrasound scanbusiness.industryObstetricsInterleukin-6Infant NewbornObstetrics and GynecologyIntact membranesPredictive valuePregnancy Trimester SecondPediatrics Perinatology and Child HealthCervix MucusPremature BirthObservational studyFemaleRisk assessmentbusinessArea under the roc curveThe journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
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Reproductive medicine and inheritance of infertility by offspring: the role of fetal programming.

2011

Objective To summarize the molecular processes involved in fetal programming, to describe how assisted reproduction technologies (ART) may affect the epigenetic pattern of the embryo, and to highlight the current knowledge of the role of perinatal events in the subsequent development of reproductive pathology affecting infertile patients. Design A literature review of fetal programming of adulthood gynecologic diseases and ART. A Medline search was performed with the following keywords: (fetal programming OR epigenetics OR methylation OR acetylation) AND (IVF OR ART) AND (gynecology). Articles up to October 2010 were selected. Articles and recent reviews were classified by human and animals…

Infertilitymedicine.medical_specialtyOffspringPopulationMEDLINEReproductive medicineBioinformaticsEpigenesis GeneticPregnancymedicineHumansEpigeneticseducationGynecologyeducation.field_of_studyFetusbusiness.industryObstetrics and GynecologyDNA Methylationmedicine.diseaseReproductive MedicinePrenatal Exposure Delayed EffectsObservational studyFemalebusinessGenital Diseases FemaleInfertility FemaleFertility and sterility
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