0000000001036214

AUTHOR

Mekki Boussaha

showing 5 related works from this author

Genome-wide detection of signatures of selection in three Valdostana cattle populations

2020

International audience; The Valdostana is a local dual purpose cattle breed developed in Italy. Three populations are recognized within this breed, based on coat colour, production level, morphology and temperament: Valdostana Red Pied (VPR), Valdostana Black Pied (VPN) and Valdostana Chestnut (VCA). Here, we investigated putative genomic regions under selection among these three populations using the Bovine 50K SNP array by combining three different statistical methods based either on allele frequencies (F-ST) or extended haplotype homozygosity (iHS and Rsb). In total, 8, 5 and 8 chromosomes harbouring 13, 13 and 16 genomic regions potentially under selection were identified by at least tw…

CoatCandidate geneMeatGenotypelocal cattle population[SDV]Life Sciences [q-bio]Quantitative Trait LociBovine BeadChip 50K; candidate genes; local cattle populations; selection signaturesRuns of HomozygosityBiologyBreedingGenomePolymorphism Single Nucleotideselection signatures03 medical and health sciencesFood AnimalsGene FrequencyAnimalsSelection GeneticGeneAllele frequencySelection (genetic algorithm)Genetic Association Studies030304 developmental biology2. Zero hungerGenetics0303 health sciencesGenomeBehavior AnimalHomozygote0402 animal and dairy sciencecandidate geneBovine BeadChip 50K04 agricultural and veterinary sciencesGeneral Medicine040201 dairy & animal sciencelocal cattle populationsMilkPhenotypeHaplotypesAnimal Science and ZoologyCattlecandidate genesSNP array
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Genomic characterization of Algerian Guelmoise cattle and their genetic relationship with other North African populations inferred from SNP genotypin…

2018

International audience; Understanding between and within-breeds genetic variability is essential in the choice of conservation management decisions for threatened populations. In this study we assessed the genetic diversity of the Algerian Guelmoise cattle (GUE) by analyzing data on 24 GUE individuals genotyped for the Illumina BovineSNP50 BeadChipv2. We also provided a detailed description of the population structure of GUE using comparisons with 23 worldwide cattle populations, selected as being representative of African, South European and indicine populations, in addition to four North African populations. We show that GUE is an admixed population which has strong genetic similarity to …

0301 basic medicine[SDV]Life Sciences [q-bio]PopulationSNPGenetic relationshipBiologyRuns of homozygosityGene flow03 medical and health sciencesAlgerian cattlePhylogeneticSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoGenetic variabilityeducationsnps2. Zero hunger[SDV.GEN]Life Sciences [q-bio]/Geneticseducation.field_of_studyGenetic diversityGeneral VeterinaryPhylogenetic tree0402 animal and dairy science04 agricultural and veterinary sciences040201 dairy & animal scienceSNP genotypingphylogenetics[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics030104 developmental biologyEvolutionary biologyVeterinary (all)Animal Science and ZoologyGenetic structureInbreeding
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Genome-Wide Analysis Reveals Selection Signatures Involved in Meat Traits and Local Adaptation in Semi-Feral Maremmana Cattle

2021

The Maremmana cattle is an ancient Podolian-derived Italian breed raised in semi-wild conditions with distinctive morphological and adaptive traits. The aim of this study was to detect potential selection signatures in Maremmana using medium-density single nucleotide polymorphism array. Putative selection signatures were investigated combining three statistical approaches designed to quantify the excess of haplotype homozygosity either within (integrated haplotype score, iHS) or among pairs of populations (Rsb and XP-EHH), and contrasting the Maremmana with a single reference population composed of a pool of seven Podolian-derived Italian breeds. Overall, the three haplotype-based analyses …

0301 basic medicineCandidate geneMaremmanaQH426-470selection signaturesdiversitySettore AGR/17 - Zootecnica Generale E Miglioramento Genetico03 medical and health sciencesGeneticslocal cattle breedsenvironmental adaptationGeneGenetics (clinical)Selection (genetic algorithm)Original ResearchLocal adaptation2. Zero hungerbiology[SDV.BA]Life Sciences [q-bio]/Animal biologyHaplotype0402 animal and dairy science04 agricultural and veterinary sciencescandidate genes; diversity; environmental adaptation; local cattle breeds; selection signaturesbiology.organism_classification040201 dairy & animal science3. Good healthlocal cattle breeds selection signatures diversity candidate genes environmental adaptation030104 developmental biologyEvolutionary biologyMolecular MedicineAdaptationcandidate genes diversity environmental adaptation local cattle breeds selection signaturescandidate genesFunction (biology)
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Genome-wide scan for selection signatures reveals novel insights into the adaptive capacity in local North African cattle

2020

International audience; Natural-driven selection is supposed to have left detectable signatures on the genome of North African cattle which are often characterized by the fixation of genetic variants associated with traits under selection pressure and/or an outstanding genetic differentiation with other populations at particular loci. Here, we investigate the population genetic structure and we provide a first outline of potential selection signatures in North African cattle using single nucleotide polymorphism genotyping data. After comparing our data to African, European and indicine cattle populations, we identified 36 genomic regions using three extended haplotype homozygosity statistic…

GenotypeEvolutionMolecular biologyQuantitative Trait Locilcsh:MedicineBreedingNorth African cattle selection signatures candidate genePolymorphism Single NucleotideArticleSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoAfrica NorthernGene FrequencyGeneticsAnimalsSelection Geneticlcsh:ScienceWhole Genome Sequencinglcsh:RGenomicsAdaptation Physiological[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal geneticsGenetics PopulationPhenotypeHaplotypeslcsh:QCattleGenome-Wide Association Study
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QTL associated to bacterial cold water disease in rainbow trout

2014

[SDV] Life Sciences [q-bio]resistancedisease[ SDV ] Life Sciences [q-bio][SDV]Life Sciences [q-bio]rainbow trout
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