0000000001036856

AUTHOR

P. Kann

showing 2 related works from this author

Konfokale Laser Scanning Mikroskopie (CLSM) kortikalen Knochens – Vergleichende Darstellung mit konventioneller Mikroskopie

1997

Materials sciencemedicine.anatomical_structureMicroscopyBiomedical EngineeringmedicineConfocal laser scanning microscopyCortical boneBiomedical engineeringBiomedizinische Technik/Biomedical Engineering
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Different muscarinic receptors mediate autoinhibition of acetylcholine release and vagally-induced vasoconstriction in the rat isolated perfused heart

1990

Experiments were carried out on rat isolated perfused hearts with both vagus nerves attached. The acetylcholine stores were labelled with [14C]-choline. The effects of muscarinic receptor antagonists on the [14C]-overflow and increase in perfusion pressure evoked by vagus nerve stimulation (10 Hz, 4-10 mA) were studied in order to determine the muscarinic receptor type involved in autoinhibition of acetylcholine release and vagally-induced vasoconstriction in the rat heart. Stimulation of the vagus nerves (1200 pulses) caused an increase in [14C]-overflow and in perfusion pressure which was significantly reduced by hexamethonium 500 mumol/l and abolished by tetrodotoxin 0.3 mumol/l or perfu…

Malemedicine.medical_specialtyBlood PressureIn Vitro Techniqueschemistry.chemical_compoundInternal medicineMuscarinic acetylcholine receptorMethoctramineMuscarinic acetylcholine receptor M4medicineAnimalsPharmacologyMyocardiumParasympatholyticsMuscarinic acetylcholine receptor M3HeartRats Inbred StrainsVagus NerveMuscarinic acetylcholine receptor M2General MedicineMuscarinic acetylcholine receptor M1Receptors MuscarinicAcetylcholineElectric StimulationRatsVagus nervePerfusionEndocrinologynervous systemchemistryVasoconstrictionAcetylcholinemedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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