0000000001037267

AUTHOR

Luis Corrales

showing 2 related works from this author

Second-Line Treatment of Non-Small Cell Lung Cancer: Clinical, Pathological, and Molecular Aspects of Nintedanib

2017

Abstract: Lung carcinoma is the leading cause of death by cancer in the world. Nowadays, most patients will experience disease progression during or after first-line chemotherapy demonstrating the need for new, effective second-line treatments. The only approved second-line therapies for patients without targetable oncogenic drivers are docetaxel, gemcitabine, pemetrexed, and erlotinib and for patients with target-specific oncogenes afatinib, osimertinib, crizotinib, alectinib, and ceritinib. In recent years, evidence on the role of antiangiogenic agents have been established as important and effective therapeutic targets in non-small cell lung cancer (NSCLC). Nintedanib is a tyrosine kinas…

0301 basic medicineOncologyAlectinibmedicine.medical_specialtyAfatinibReview03 medical and health scienceschemistry.chemical_compoundangiogenesis0302 clinical medicineInternal medicinemedicinenintedanibOsimertinibnon-small cell lung cancerclinical trialsCeritinibCrizotinibbusiness.industrytarget therapyangiogenesiclinical trialGeneral Medicinerespiratory tract diseases030104 developmental biologyDocetaxelchemistry030220 oncology & carcinogenesissecond-line treatmentMedicineangiogenesis; clinical trials; nintedanib; non-small cell lung cancer; second-line treatment; target therapyNintedanibErlotinibHuman medicinebusinessmedicine.drug
researchProduct

Morphological and Biometric Features of Male BluethroatsLuscinia svecicain Central Iberia

2011

Summary. In order to test biometrics and plumage variability in bluethroats Luscinia svecica in central Iberia, 185 birds were captured in four areas (Sierra-Bejar, Sierra-Piedrahita, Sierra-Gredos and Sierra-Paramera). Older bluethroats were significantly larger than second calendar year birds in wing, tail, and total body lengths, but not in tarsus and bill lengths. A multivariate analysis of variance (MANOVA) and a principal component analysis (PCA) were used. Total body length only varied significantly between sampling areas: the birds from Sierra-Bejar were larger than those from Sierra-Gredos and Sierra-Paramera, but were similar to those of Sierra-Piedrahita. Birds with a white spot,…

Total Body LengthWingBiometricsPlumageEcologyLusciniaZoologyAnimal Science and ZoologyTotal bodyBiologySubspeciesbiology.organism_classificationEcology Evolution Behavior and SystematicsArdeola
researchProduct