0000000001050089
AUTHOR
M Gatto
Do patients' and referral centers' characteristics influence multiple sclerosis phenotypes? Results from the Italian multiple sclerosis and related disorders register
Abstract Background Multiple sclerosis (MS) is characterized by phenotypical heterogeneity, partly resulting from demographic and environmental risk factors. Socio-economic factors and the characteristics of local MS facilities might also play a part. Methods This study included patients with a confirmed MS diagnosis enrolled in the Italian MS and Related Disorders Register in 2000–2021. Patients at first visit were classified as having a clinically isolated syndrome (CIS), relapsing–remitting (RR), primary progressive (PP), progressive-relapsing (PR), or secondary progressive MS (SP). Demographic and clinical characteristics were analyzed, with centers’ characteristics, geographic macro-ar…
The Italian multiple sclerosis register
The past decade has seen extraordinary increase in worldwide availability of and access to several large multiple sclerosis (MS) databases and registries. MS registries represent powerful tools to provide meaningful information on the burden, natural history, and long-term safety and effectiveness of treatments. Moreover, patients, physicians, industry, and policy makers have an active interest in real-world observational studies based on register data, as they have the potential to answer the questions that are most relevant to daily treatment decision-making. In 2014, the Italian MS Foundation, in collaboration with the Italian MS clinical centers, promoted and funded the creation of the …
The lexicon of community acquis: how to negotiate the non-negotiable
In the context of the activities aimed to improve and develop the integration and cooperation of new Member States together with the states already belonging to the European Community, EU institutions have carried out a number of measures to increase the coherence of the body of common rights and obligations, binding all the Member States of the European Union (community acquis), for a long time. For this reason, the Commission of the European Community began in 2001 a process of consultation and discussion about the way in which problems resulting from the lack of a correspondence between national contract laws (and related terms) belonging to different legal systems should be dealt with a…