0000000001056232

AUTHOR

Karsten Kristiansen

showing 2 related works from this author

Profiling of lipid species by normal-phase liquid chromatography, nanoelectrospray ionization, and ion trap–orbitrap mass spectrometry

2013

Detailed analysis of lipid species can be challenging due to their structural diversity and wide concentration range in cells, tissues, and biofluids. To address these analytical challenges, we devised a reproducible, sensitive, and integrated lipidomics workflow based on normal-phase liquid chromatography-Fourier transform mass spectrometry (LC-FTMS) and LC-ITMS(2) (ion trap tandem mass spectrometry) for profiling and structural analysis of lipid species. The workflow uses a normal-phase LC system for efficient separation of apolar and polar lipid species combined with sensitive and specific analysis powered by a chip-based nanoelectrospray ion source and a hybrid ion trap-orbitrap mass sp…

Spectrometry Mass Electrospray IonizationCeramideBiophysicsAnalytical chemistryCeramidesTandem mass spectrometryMass spectrometryOrbitrapBiochemistrylaw.inventionMicechemistry.chemical_compoundTandem Mass Spectrometrylaw3T3-L1 CellsCerebellumIonizationLipidomicsAnimalsMolecular BiologyTriglyceridesChromatographyChemistryCell BiologyIon sourceMice Inbred C57BLIon trapHydrophobic and Hydrophilic InteractionsChromatography LiquidAnalytical Biochemistry
researchProduct

Disease sytems chemical biology of flavors

2012

International audience

[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[SDV.AEN]Life Sciences [q-bio]/Food and NutritionComputingMilieux_MISCELLANEOUS
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