0000000001069381

AUTHOR

T. G. Teoh

showing 2 related works from this author

Characterization of neutrophil subsets in healthy human pregnancies

2014

We have previously shown that in successful pregnancies increased arginase activity is a mechanism that contributes to the suppression of the maternal immune system. We identified the main type of arginase-expressing cells as a population of activated low-density granulocytes (LDGs) in peripheral blood mononuclear cells and in term placentae. In the present study, we analyzed the phenotype of LDGs and compared it to the phenotype of normal density granulocytes (NDGs) in maternal peripheral blood, placental biopsies and cord blood. Our data reveal that only LDGs but no NDGs could be detected in placental biopsies. Phenotypically, NDGs and LDGs from both maternal and cord blood expressed diff…

NeutrophilsPlacentaEnzyme Metabolismlcsh:MedicineGene ExpressionBiochemistryCell DegranulationNeutrophil ActivationImmune toleranceLeukocyte Count0302 clinical medicineImmunophenotypingPregnancyMolecular Cell BiologySUPPRESSOR-CELLSlcsh:Science0303 health scienceseducation.field_of_studyMultidisciplinaryL-ARGININEObstetrics and GynecologyFetal BloodInnate Immunity3. Good healthEnzymesmedicine.anatomical_structurePhenotypeARGINASE ACTIVITYCord bloodMedicineScience & Technology - Other TopicsFemaleBiological MarkersTHERAPEUTIC PERSPECTIVESResearch ArticleEXPRESSIONAdultCordGeneral Science & TechnologyImmune CellsPopulationImmunologyBiologyMETABOLISMGRANULOCYTESGPI-Linked ProteinsPeripheral blood mononuclear cellMECHANISMSImmunophenotyping03 medical and health sciencesImmune systemAntigens CDPlacentaMD MultidisciplinarymedicineImmune ToleranceHumansCell LineageeducationBiology030304 developmental biologyScience & TechnologyArginaseMULTIDISCIPLINARY SCIENCESlcsh:RImmunityOXIDANT RELEASEImmunologyWomen's Healthlcsh:QClinical ImmunologyIMMUNE-SYSTEMCell Adhesion MoleculesCytometryBiomarkers030215 immunology
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The effect of gestational age and cervical length measurements in the prediction of spontaneous preterm birth in twin pregnancies : an individual pat…

2016

OBJECTIVE: To assess the effect of gestational age (GA) and cervical length (CL) measurements at transvaginal ultrasound (TVUS) in the prediction of preterm birth in twin pregnancy. DESIGN: Individual patient data (IPD) meta-analysis. SETTING: International multicentre study. POPULATION: Asymptomatic twin pregnancy. METHODS: MEDLINE and EMBASE searches were performed and IPD obtained from authors of relevant studies. Multinomial logistic regression analysis determined probabilities for birth at ≤28(+0) , 28(+1) to 32(+0) , 32(+1) to 36(+0) , and ≥36(+1) weeks as a function of GA at screening and CL measurements. MAIN OUTCOME MEASURES: Predicted probabilities for preterm birth at ≤28(+0) , 2…

medicine.medical_specialtyPopulationGestational AgeCervix UteriReviewResearch Support03 medical and health sciences0302 clinical medicinePredictive Value of TestsPregnancymedicineJournal ArticleHumans030212 general & internal medicineNon-U.S. Gov'teducationTwin PregnancyGynecologyeducation.field_of_studyPregnancy030219 obstetrics & reproductive medicinebusiness.industryObstetricsResearch Support Non-U.S. Gov'tprematurityTwinObstetrics and GynecologyGestational agepreterm birthtwin pregnancymedicine.diseaseCervical Length MeasurementMulticenter Studyindividual patient meta-analysisPremature birthCervical Length MeasurementPredictive value of testsPregnancy TwinGestationPremature BirthFemalebusinessCervical lengthMeta-Analysis
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