Author: Giulia Costanza Leonardi

0000000001074786

AUTHOR

Giulia Costanza Leonardi

showing 1 related works from this author

Ageing: from inflammation to cancer.

2018

Abstract Ageing is the major risk factor for cancer development. Hallmark of the ageing process is represented by inflammaging, which is a chronic and systemic low-grade inflammatory process. Inflammation is also a hallmark of cancer and is widely recognized to influence all cancer stages from cell transformation to metastasis. Therefore, inflammaging may represent the biological phenomena able to couple ageing process with cancer development. Here we review the molecular and cellular pathway involved in age-related chronic inflammation along with its potential triggers and their connection with cancer development.

0301 basic medicineSenescencelcsh:Immunologic diseases. AllergyAgingCellImmunologyAgeing; Cancer; DAMPs; Inflammation; MiRna; Microbiota; Obesity; SenescenceInflammationReviewlcsh:GeriatricsSenescenceMetastasis03 medical and health sciencesmicroRNAMedicineDAMPObesityCancerSettore MED/04 - Patologia GeneraleInflammationDAMPsbusiness.industryAgeing; Cancer; DAMPs; Inflammation; Microbiota; MiRna; Obesity; Senescence; Immunology; AgingMicrobiotaCancermedicine.diseaselcsh:RC952-954.6Ageing030104 developmental biologymedicine.anatomical_structureAgeingCancer researchSettore MED/26 - NeurologiaCancer developmentmedicine.symptombusinesslcsh:RC581-607MiRna

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PEPhysical Sciences and Engineering
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