0000000001075368
AUTHOR
R. Toledo
14th International HLA and Immunogenetics Workshop: Report on the Prospective Chronic Rejection Project
An international collaborative study of 45 transplant centers was undertaken at the 14th International HLA (human leukocyte antigen) and Immunogenetics Workshop to see if HLA antibodies detected posttransplant are predictive of chronic graft failure. With the newly developed assay, MICA (major histocompatibility complex class I-related chain A) antibodies were also measured and their effect analyzed. Total of 5219 sera from patients who were more than 6 months posttransplant with functioning graft were tested for HLA antibodies by enzyme-linked immunosorbent assay, flow cytometry, or Luminex. HLA antibodies were found in 27.2% of kidney patients, 23.6% in the liver, 52.7% in the heart, and …
Helminth-Trematode: Echinostoma
The term, echinostomes, includes those digeneans belonging to the family Echinostomatidae. Echinostomes are a rather heterogeneous group of cosmopolitan hermaphroditic digeneans that inhabit, as adults, the intestine of a great spectrum of vertebrate hosts, such as birds, mammals and, occasionally, reptiles and fishes. They can also parasitize humans causing the food-borne infection called echinostomiasis. The definitive hosts become infected after ingestion of the second intermediate host harboring the encysted metacercariae. Clinical symptoms of echinostomiasis include abdominal pain, violent watery diarrhea, and anorexia. The disease occurs focally and transmission is linked to fresh or …