Total Variation Regularization in Digital Breast Tomosynthesis

We developed an iterative algebraic algorithm for the reconstruction of 3D volumes from limited-angle breast projection images. Algebraic reconstruction is accelerated using the graphics processing unit. We varied a total variation (TV)-norm parameter in order to verify the influence of TV regularization on the representation of small structures in the reconstructions. The Barzilai-Borwein algorithm is used to solve the inverse reconstruction problem. The quality of our reconstructions was evaluated with the Quart Mam/Digi Phantom, which features so-called Landolt ring structures to verify perceptibility limits. The evaluation of the reconstructions was done with an automatic LR detection a…