0000000001080846

AUTHOR

Carlos Jiménez

showing 6 related works from this author

Unpublished Mediterranean records of marine alien and cryptogenic species

2020

Este artículo contiene 18 páginas, 4 figuras.

Invasions biològiques -- Mediterrània (Mar)geo-referenced records0206 medical engineeringNon-native speciesInvasive alien speciesLibrary sciencenon-native species non-indigenous distribution citizen science invasive alien species geo-referenced records Mediterranean Sea02 engineering and technologyAlienDistributionCitizen science01 natural sciencesRecords -- ManagementScience -- Mediterranean Region0103 physical sciencesAgency (sociology)citizen scienceCitizen sciencedistributionMediterranean Seamedia_common.cataloged_instancenon-indigenousZoología14. Life underwaterEuropean unionnon-indigenous speciesComputingMilieux_MISCELLANEOUSEcology Evolution Behavior and SystematicsGlobal environmental analysismedia_commonBiological invasions -- Mediterranean Seainvasive alien species010304 chemical physicsEcologySettore BIO/02 - Botanica SistematicaMarine reservenon-native speciesGeo-referenced records020601 biomedical engineeringEspècies introduïdes -- Mediterrània (Mar)Introduced organisms -- Mediterranean Sea13. Climate actionGeneral partnership[SDE]Environmental SciencesMarine protected areaCitizen science; Distribution; Geo-referenced records; Invasive alien species; Mediterranean Sea; Non-indigenous; Non-native speciesNon-indigenousScience -- Methodology -- Case studies
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Polar marine biology science in Portugal and Spain: Recent advances and future perspectives

2013

Xavier, José C. et al.

Polar science0106 biological sciencesEcology (disciplines)BiodiversityClimate changeAquatic ScienceOceanography010603 evolutionary biology01 natural sciencesArcticMarine ecosystem14. Life underwaterMedio MarinoCentro Oceanográfico de GijónEcology Evolution Behavior and SystematicsApex predatorMarine biologyPortugalEcology010604 marine biology & hydrobiologyPelagic zoneMarine Biology (journal)Marine SciencesGeographyArcticSpain13. Climate actionAntarctic
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The Role of Phospholipase D and MAPK Signaling Cascades in the Adaption of Lichen Microalgae to Desiccation: Changes in Membrane Lipids and Phosphopr…

2016

Classically, lichen phycobionts are described as poikilohydric organisms able to undergo desiccation due to the constitutive presence of molecular protection mechanisms. However, little is known about the induction of cellular responses in lichen phycobionts during drying. The analysis of the lipid composition of the desiccated lichen microalga Asterochloris erici revealed the unusual accumulation of highly polar lipids (oligogalactolipids and phosphatidylinositol), which prevents the fusion of membranes during stress, but also the active degradation of cone-shaped lipids (monogalactosyldiacylglycerol and phosphatidylethanolamine) to stabilize membranes in desiccated cells. The level of pho…

0106 biological sciences0301 basic medicineMAPK/ERK pathwayLichensPhysiologyMAP Kinase Signaling SystemMembrane lipidsPlant ScienceBiology01 natural sciencesDesiccation toleranceDephosphorylation03 medical and health scienceschemistry.chemical_compoundMembrane LipidsChlorophytaOsmotic PressureMicroalgaePhospholipase DPhosphorylationProtein kinase ADehydrationPhospholipase DKinaseCell BiologyGeneral MedicinePhosphatidic acidPhosphoproteinsAdaptation Physiological030104 developmental biologychemistryBiochemistrylipids (amino acids peptides and proteins)010606 plant biology & botanyPlantcell physiology
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Rapid progression from oral leukoplakia to carcinoma in an immunosuppressed liver transplant recipient

2002

Immunosuppression used to avoid graft rejection in solid organ transplantation recipients leads to a variety of side-effects, and an increased rate of infections and de novo malignancies. Oral conditions usually associated with immunosuppressive drugs include fungal and viral infection, and lip lesions, but intra-oral carcinoma has not been reported as having a high incidence. This report deals with a male liver transplant recipient receiving FK506 (5 mg/day) and prednisone (20 mg/day) who was diagnosed with a homogeneous leukoplakia on the floor of the mouth 4 months after transplantation, and 4 months later with a squamous cell carcinoma growth at the site of this lesion. The rapid transf…

MaleCancer Researchmedicine.medical_specialtyPathologymedicine.medical_treatmentGastroenterologyTacrolimusLesionPrednisoneInternal medicinemedicineCarcinomaHumansRisk factorLeukoplakiaImmunosuppression Therapybusiness.industryCancerImmunosuppressionMiddle Agedmedicine.diseaseLiver TransplantationTransplantationstomatognathic diseasesOncologyCarcinoma Squamous CellDisease ProgressionPrednisoneMouth NeoplasmsLeukoplakia OralOral Surgerymedicine.symptombusinessImmunosuppressive Agentsmedicine.drugOral Oncology
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The oral KIF11 inhibitor 4SC‐205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma …

2021

Inhibidor de KIF11; Terapias dirigidas; Metástasis Inhibidor de KIF11; Teràpies dirigides; Metàstasi KIF11 inhibitor; Targeted therapies; Metastasis In summary, our study provides a rationale for the future therapeutic integration in clinical trials of 4SC-205, an structurally distinct oral KIF11 inhibitor that shows potent antitumor activity in multiple preclinical neuroblastoma models and sensitizes neuroblastoma cells to standard chemotherapy and specific neuroblastoma-targeted therapies. The financial support for this research was provided by Instituto de Salud Calos III (PI20/00530 to Miguel F. Segura; PI20/01107 to Rosa Noguera; PI17/02248 and CPII18/00027 to Anna Santamaria; PI19/013…

Medicine (General)Neuroblastoma - Tractament:neoplasias::neoplasias por tipo histológico::neoplasias de células germinales y embrionarias::tumores neuroectodérmicos::neoplasias neuroepiteliales::tumores neuroectodérmicos primitivos::tumores neuroectodérmicos primitivos periféricos::neuroblastoma [ENFERMEDADES]Metastatic neuroblastomaMedicació oralMedicaments antineoplàstics - Ús terapèutic:Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores]Medicine (miscellaneous)Administration OralKinesinsAntineoplastic Agents:Other subheadings::Other subheadings::/drug therapy [Other subheadings]Letter to Editor:Neoplasms::Neoplasms by Histologic Type::Neoplasms Germ Cell and Embryonal::Neuroectodermal Tumors::Neoplasms Neuroepithelial::Neuroectodermal Tumors Primitive::Neuroectodermal Tumors Primitive Peripheral::Neuroblastoma [DISEASES]MiceNeuroblastomaR5-920Cell Line Tumor:terapéutica::farmacoterapia::vías de administración de medicamentos::administración oral [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]MedicineAnimalsHumansAntitumor activityPrimary (chemistry)business.industry:acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antineoplásicos [COMPUESTOS QUÍMICOS Y DROGAS]Disease Models Animal:Therapeutics::Drug Therapy::Drug Administration Routes::Administration Oral [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Cancer researchMolecular Medicine:Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents [CHEMICALS AND DRUGS]businessClinical and Translational Medicine
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Recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (Covid-19) en pacientes con trasplante renal

2020

The SARS-CoV-2 (Covid-19) coronavirus pandemic is evolving very quickly and means a special risk for both immunosuppressed and comorbid patients. Knowledge about this growing infection is also increasing although many uncertainties remain, especially in the kidney transplant population. This manuscript presents a proposal for action with general and specific recommendations to protect and prevent infection in this vulnerable population such as kidney transplant recipients. Resumen: La pandemia por coronavirus SARS-CoV-2 (Covid-19) está evolucionando de manera muy rápida y representa un riesgo especial en pacientes inmunodeprimidos y con comorbilidades añadidas. El conocimiento sobre esta in…

:Phenomena and Processes::Immune System Phenomena::Immunocompromised Host [Medical Subject Headings]:Anatomy::Urogenital System::Urinary Tract::Kidney [Medical Subject Headings]Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Population030230 surgerylcsh:RC870-923medicine.disease_causeKidney transplant:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Kidney transplantation03 medical and health sciences0302 clinical medicine:Health Care::Health Care Quality Access and Evaluation::Quality of Health Care::Epidemiologic Factors::Comorbidity [Medical Subject Headings]PandemicCOVID-19 ; inmunodeprimido ; trasplante renal ; kidney transplantation ; immunosuppressed ; SARS-CoV-2MedicineVulnerable population030212 general & internal medicineeducationKidney transplantationCoronavirus:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]education.field_of_studyInmunodeprimidoSARS-CoV-2business.industry:Health Care::Environment and Public Health::Public Health::Disease Outbreaks::Epidemics::Pandemics [Medical Subject Headings]lcsh:Diseases of the genitourinary system. Urologymedicine.diseaseVirology:Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [Medical Subject Headings]Trasplante renalImmunosuppressedNephrology:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Immunologic Factors::Immunosuppressive Agents [Medical Subject Headings]Covid-19businessNefrología (English Edition)
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