Aneuploidy as a consequence of senescence and ovariectomy in the golden hamster (Mesocricetus auratus).

1978

The hypothesis of the preferred X-chromosome loss in elder human females was reevaluated in the golden hamster: early castration of females proved that the increase of aneuploid cells is correlated with the loss of the ovaries. But here, and in old females, aneuploidy consisted of random loss of excess of chromosomes, in no case an X-chromosome.