6533b85cfe1ef96bd12bcb5e

RESEARCH PRODUCT

Aneuploidy as a consequence of senescence and ovariectomy in the golden hamster (Mesocricetus auratus).

J WeilerW Sachsse

subject

Senescencemedicine.medical_specialtyAgingX ChromosomeAneuploidyBone Marrow CellsBiologyAndrologyCellular and Molecular Neurosciencechemistry.chemical_compoundInternal medicineCricetinaemedicineAnimalsCastrationMolecular BiologyX chromosomePharmacologyCell Biologymedicine.diseasebiology.organism_classificationAneuploidyEndocrinologyCastrationchemistryMolecular MedicineAneuploid CellsFemaleHuman FemalesMesocricetusGolden hamster

description

The hypothesis of the preferred X-chromosome loss in elder human females was reevaluated in the golden hamster: early castration of females proved that the increase of aneuploid cells is correlated with the loss of the ovaries. But here, and in old females, aneuploidy consisted of random loss of excess of chromosomes, in no case an X-chromosome.

10.1007/bf01923019https://pubmed.ncbi.nlm.nih.gov/631259