Inflamm-aging ed immunosenescenza

Nell’anziano sono descritte alterazioni dell’immunità naturale ed acquisita generalmente percepite come una condizione di deterioramento del sistema immune. A questa condizione si affianca anche uno stato infiammatorio cronico, configurando la cosiddetta immunosenescenza, che diventa il principale responsabile dell’insorgenza di patologie a carattere infettivo ed infiammatorio età correlate. Certamente una migliore conoscenza dell’immunosenescenza e lo sviluppo di adeguate strategie per contrastarla sono essenziali per migliorare la qualità della vita degli anziani e per permettere la formulazione di strategie anti-invecchiamento finalizzate non tanto a «ringiovanire» l’individuo, ma a rita…

Il Core Curriculum degli studi di Medicina. Stato dell'arte e prospettive

Thrombotic thrombocytopenic purpura: a review of the literature in the light of our experience with plasma exchange

Biomarkers of aging

Aging is a complex process that negatively impacts the development of the different systems and its ability to function. Moreover, the Aging rate in humans is not the same, principally due to genetic heterogeneity and environmental factors. The aging rate is measured as the decline of functional capacity and stress resistance. Therefore, several attempts have been made to analyse the individual age, ( so-called biological age) compared to chronological age. The biomarkers of aging are age-related body function or composition, these markers aim to assess the biological age and predict the onset of age-related diseases and/or residual lifetime. Such biomarkers should help in one hand to chara…

MOLECULAR AND CELLULAR APPROACHES IN TRANSFUSION MEDICINE

Insegnare nelle Università la Fitoterapia e l’Agopuntura?

According to National Center for Complementary and Alternative Medicine (CAM) of NIH, the CAM terms are used to mean the array of health care approaches with a history of use or origins outside of mainstream medicine. Numerous surveys document high level of interest in use of CAM among the Western public, hence raising the matter of their study in the medical education. Several scientists have subjected CAM interventions to the same methodological scrutiny responsible for the progress of Western clinical medicine (that is evidence based), i.e. with the standard of randomized controlled trials. So, the purpose of this paper was to review the scientific evidences of two particular CAM, Phytot…