0000000001089281
AUTHOR
F. Gabriel
Clasificación y tratamiento de la embolia pulmonar aguda
Resumen El empleo de escalas clinicas, ecocardiografia, angiografia toracica computarizada, biomarcadores y electrocardiograma permite clasificar la embolia pulmonar aguda en masiva, submasiva y de bajo riesgo con el objetivo de poder administrar al paciente el tratamiento adecuado. En ausencia de contraindicaciones deben tratarse inicialmente con heparinas de bajo peso molecular, fondaparinux o heparinas no fraccionadas. La trombolisis es el tratamiento de eleccion en la embolia pulmonar masiva al tener un riesgo aceptable de complicaciones hemorragicas. La trombectomia percutanea y la embolectomia quirurgica son tratamientos efectivos en la embolia masiva o submasiva con disfuncion ventri…
Usefulness of Thrombophilia Testing in Venous Thromboembolic Disease
Information on thrombophilia risk factors for patients with upper extremity deep vein thrombosis (UEDVT) is limited. The genetic, acquired, and coagulation risk factors of an acute episode of lower EDVT (LEDVT) or UEDVT, either isolated or associated with pulmonary embolism (PE), were studied.A total of 4503 patients participated in a thrombophilia study. Odds ratio (OR) and 95% confidence intervals (CIs) were calculated.Mean age of the participants was 55 ± 19 years. The risk of LEDVT or UEDVT, isolated or associated with PE, was calculated according to thrombophilia factors. We found association between LEDVT and factor V Leiden ([FVL]; OR: 1.8; 95% CI 1.4-2.4) and resistance to activated…