0000000001096183

AUTHOR

Armands Sīviņš

showing 3 related works from this author

Lack of Association Between Rs2067474 Polymorphism in the Histamine Receptor H2 Gene and Gastric Cancer In Latvian Population

2018

Abstract Histamine has an important role in the process of the gastric mucosa inflammation acting via histamine receptor H2 (encoded by the gene HRH2). Single nucleotide polymorphism of the enhancer element of HRH2 gene promoter rs2067474 (1018G>A)may be associated with changes of expression of the receptor. We attempted to clarify the association of this polymorphism with gastric cancer and/or atrophic gastritis in the Latvian (Caucasian) population. The study group consisted of 121 gastric cancer patients and 650 patients with no evidence of gastric neoplasia on upper gastrointestinal endoscopy. Genotyping for rs2067474 was performed with the TaqMan probe-based system using a commercia…

medicine.medical_specialtyAtrophic gastritisSciencePopulationSingle-nucleotide polymorphismhistamine h2 receptorGastroenterologychemistry.chemical_compoundHistamine receptorInternal medicineGenotypeGastric mucosagenetic polymorphismMedicineeducationGenotypingeducation.field_of_studyMultidisciplinarybusiness.industrygastric cancerQmedicine.diseasemedicine.anatomical_structurechemistrychronic gastritisbusinessHistamineProceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.
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Successful Extensive Multiorgan Resection of Malignant Duodenal Tumor: A Case Report

2020

Summary Duodenal adenocarcinoma is one of the rarest tumours of all gastrointestinal malignancies. Due to rarity and late symptoms, duodenal cancers are diagnosed in late stage, but overall survival rate is high. We present a case of locally advanced duodenal adenocarcinoma with successful surgical treatment including multiorgan resection.

medicine.medical_specialtybusiness.industryMalignant Duodenal TumormedicineGeneral Materials ScienceRadiologybusinessdigestive system diseasesResectionActa Chirurgica Latviensis
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KUŅĢA VĒŽA ĶIRURĢISKĀS ĀRSTĒŠANAS REZULTĀTU UN KVALITĀTES RĀDĪTĀJU ANALĪZE

2012

ANOTĀCIJA. Pētījumā tika analizēti kuņģa vēža pacientu dzīvildzi ietekmējoši riska faktori: komplikācijas, paaugstināts ķermeņa masas indekss, splenektomijas, asins pārliešanas un operācijas laikā izdalīto limfmezglu skaita atvasināts parametrs – N attiecība (metastātisko un izmeklēto limfmezglu attiecība), SIA Rīgas Austrumu klīniskās universitātes slimnīcas stacionāra Latvijas Onkoloģijas centrā radikāli operētiem kuņģa vēža pacientiem. Rezultāti: Nav nozīmīgas dzīvildzes atšķirības starp pN1 un pN2 pacientu grupām pēc TNM klasifikācijas. Izmantojot N attiecību (1–25% vs. 30 10,5% (p=0,195), sakarība starp ĶMI un komplikācijām nebija statistiski ticama (p=0,152). Kaplan-Meier līknes parād…

OnkoloģijaOncologyMedicineMedicīna un farmācijaVeselības aprūpeMedicīna
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