0000000001096949

AUTHOR

M P Fantini

showing 2 related works from this author

Paving the way of systems biology and precision medicine in allergic diseases: the Me DALL success story

2016

MeDALL (Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015) has proposed an innovative approach to develop early indicators for the prediction, diagnosis, prevention and targets for therapy. MeDALL has linked epidemiological, clinical and basic research using a stepwise, large-scale and integrative approach: MeDALL data of precisely phenotyped children followed in 14 birth cohorts spread across Europe were combined with systems biology (omics, IgE measurement using microarrays) and environmental data. Multimorbidity in the same child is more common than expected by chance alone, suggesting that these diseases share causal mechanisms irrespective of IgE sen…

0301 basic medicineAllergyeducation.field_of_studybusiness.industrySystems biologyImmunologyPopulationAtopic dermatitisOmicsmedicine.diseasePrecision medicine3. Good healthReview article03 medical and health sciences030104 developmental biology0302 clinical medicine030228 respiratory systemImmunologyImmunology and AllergyMedicinemedia_common.cataloged_instanceEuropean unionbusinesseducationmedia_commonAllergy
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Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU…

2016

MeDALL (Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015) has proposed an innovative approach to develop early indicators for the prediction, diagnosis, prevention and targets for therapy. MeDALL has linked epidemiological, clinical and basic research using a stepwise, large-scale and integrative approach: MeDALL data of precisely phenotyped children followed in 14 birth cohorts spread across Europe were combined with systems biology (omics, IgE measurement using microarrays) and environmental data. Multimorbidity in the same child is more common than expected by chance alone, suggesting that these diseases share causal mechanisms irrespective of IgE sen…

asthma; IgE; multimorbidity; polysensitization; rhinitis.
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