Status and prospects of systems biology in grapevine research

The cultivated grapevine, Vitis vinifera L., has gathered a vast amount of omics data throughout the last two decades, driving the imperative use of computational resources for its analysis and integration. Molecular systems biology arises from this need allowing to model and predict the emergence of phenotypes or responses in biological systems. Beyond single omics networks, integrative approaches associate the molecular components of an organism and combine them into higher order networks to model dynamic behaviors. Application of network-based methods in multi-omics data is providing additional resources to address important questions regarding grapevine fruit quality and composition. He…