0000000001104815

AUTHOR

M. O. The

showing 2 related works from this author

External validation of the preoperative Karakiewicz nomogram in a large multicentre series of patients with renal cell carcinoma

2012

Purpose: To perform a formal external validation of the preoperative Karakiewicz nomogram (KN) for the prediction of cancer-specific survival (CSS) using a large series of surgically treated patients diagnosed with organ-confined or metastatic renal cell carcinoma (RCC). Methods: Patient population originated from a series of retrospectively gathered cases that underwent radical or partial nephrectomy between years 1995 and 2007 for suspicion of kidney cancer. The original Cox coefficients were used to generate the predicted risk of CSS at 1, 2, 5, and 10 years following surgery and compared to the observed risk of CSS in the current population. External validation was quantified using meas…

Malemedicine.medical_treatmentKarakiewicz NomogramPredictive Value of TestNephrectomyNomogramPreoperative nomogram; Renal cell carcinoma; Prognostic Factors; Partial Nephrectomy; Radical nephrectomy; Metastatic renal cell carcinomaRisk FactorsRenal cell carcinomaRetrospective StudieChildAged 80 and overeducation.field_of_studyRadical nephrectomyPrognostic FactorKidney NeoplasmMiddle AgedKidney NeoplasmsNephrectomyRenal cell carcinomaSurvival RateItalyPreoperative nomogramPredictive value of testsPreoperative PeriodFemalePartialHumanAdultmedicine.medical_specialtyKarakiewicz Nomogram; Renal cell carcinoma; cancer specific survivalAdolescentUrologyPopulationMetastatic renal cell carcinomacancer specific survivalUrologyYoung AdultPredictive Value of TestsmedicineHumanseducationSurvival rateCarcinoma Renal CellRetrospective StudiesAgedPrognostic Factorsbusiness.industryRisk FactorRetrospective cohort studyNomogramMetastatic renal cell carcinoma; Nephrectomy; Preoperative nomogram; Prognostic Factors; Renal cell carcinomamedicine.diseaseNomogramsbusinessKidney cancer
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Elective partial nephrectomy is equivalent to radical nephrectomy in patients with clinical T1 renal cell carcinoma: results of a retrospective, comp…

2012

Study Type - Therapy (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Few studies supported the expanded indications for nephron-sparing surgery (NSS) in selected patients with 4.1 cm renal tumours in the size range (T1b). However, all these comparative studies included both imperative and elective partial nephrectomy and patient selection for analysis was based on pathological stage (pT1) and not on clinical stage (cT1). Patients with clinically organ-confined RCC (cT1) who are candidates for elective PN have a limited risk of clinical understaging. NSS is not associated with an increased risk of recurrence and cancer-specific mortality both in cT1a a…

Malerenal cell carcinomapartial nephrectomyrenal cancerNephrectomymethodsElectiveclinical staging; nephron-sparing surgery; partial nephrectomy; radical nephrectomy; renal cancernephrectomyclinical stagingHumansCarcinoma Renal CellSurgical ProceduresElective Surgical ProcedureCarcinomanephron-sparing surgeryRenal CellElective partial nephrectomy is equivalent to radical nephrectomy in patients with clinical T1 renal cell carcinomaKidney NeoplasmMiddle AgedKidney NeoplasmsSurvival Ratemortality/pathology/surgeryElective Surgical Proceduresnephrectomy; renal cell carcinoma; nephron-sparing surgeryFemaleCarcinoma; Renal Cell; mortality/pathology/surgery Female Humans Kidney Neoplasms; mortality/pathology/surgery Male Middle Aged Nephrectomy; methods Surgical Procedures; Elective Survival RateHumanradical nephrectomy
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