0000000001108976
AUTHOR
G Candiano
Investigation of applicability of alanine pellets and films for dosimetry of proton clinical beams
Laser-driven proton has recently gained a great interest as an alternative to conventional and more expensive acceleration techniques. These ion beams have desirable qualities such as small source size, high luminosity and small emittance to be used in different physics fields. This is very promising specially for the future perspective of a new concept of hadrontherapy based on laser-based devices could be developed, replacing traditional accelerating machines. ELIMED (Medical Applications at Extreme Light Infrastructure) is a task-force originally born by an idea of ELI-Beams (Prague) and INFN-LNS (Italian Institute for Nuclear Physics of Catania) researchers. ELIMED main goal is to perfo…
Alanine/ESR dosimetry for electron Intra-Operative RadioTherapy: output factor measurements and Monte Carlo-GEANT4 simulations for IORT mobile dedicate accelerator
Intra-operative radiation therapy (IORT) is a treatment modality where a single high dose of radiation is delivered directly to the tumor bed or to the exposed tumor during the surgical intervention, while avoiding surrounding dose-limiting structures. Mobile electron linear accelerators dedicated to IORT have been manufactured which have promoted a local large diffusion of this radiotherapy modality. For breast irradiation, a single fraction of 21 Gy delivered on the target volume during the surgical procedure is equivalent to the total dosage (60 Gy) usually delivered during 30 external fractionated radiotherapy at 2Gy/fraction. Alternatively, a single dose of 10 Gy can be administered as…