Incidence of Narcolepsy in Germany

Study objectives Following the 2009 pandemic, reports of an association between an AS03 adjuvanted H1N1 pandemic influenza vaccine and narcolepsy were published. Besides determining background incidence rates for narcolepsy in Germany this study aimed at investigating whether there was a change in incidence rates of narcolepsy between the pre-pandemic, pandemic, and the post-pandemic period on the population level. Design Retrospective epidemiological study on the incidence of narcolepsy with additional capture-recapture analysis. Setting German sleep centers. Patients or participants Eligible were patients with an initial diagnosis of narcolepsy (ICD10 Code G47.4) within the period from Ja…