0000000001117739

AUTHOR

Amparo Lanuza

showing 2 related works from this author

Effects of cigarette smoke on methacholine- and AMP-induced air trapping in asthmatics.

2014

Abstract Objective: No information is available on the effect of cigarette smoke on bronchoconstrictor-induced air trapping in asthma. The aim of this study was to evaluate the additional influence of smoking on methacholine- and adenosine 5'-monophosphate (AMP)-induced air trapping in subjects with asthma.Airway responsiveness to methacholine and AMP, bronchial (J'awNO) and alveolar (CANO) nitric oxide (NO) and exhaled breath condensate pH were measured in 68 adults (23 current smokers with asthma, 23 non-smokers with asthma and 22 current or former smokers with chronic obstructive pulmonary disease; COPD). The degree of air trapping induced by each bronchoconstrictor agent was expressed b…

Pulmonary and Respiratory MedicineAdultMaleVital capacityVital CapacityAir trappingNitric OxideBronchoconstrictor AgentsFEV1/FVC ratioPulmonary Disease Chronic Obstructiveimmune system diseasesSmokeTobaccomedicineImmunology and AllergyHumansExhaled breath condensateMethacholine ChlorideAsthmaCOPDbusiness.industrySmokingrespiratory systemMiddle Agedmedicine.diseaseAdenosine MonophosphateAsthmarespiratory tract diseasesBreath TestsAnesthesiaPediatrics Perinatology and Child HealthExhaled nitric oxideMethacholineFemalemedicine.symptombusinessmedicine.drugThe Journal of asthma : official journal of the Association for the Care of Asthma
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Airway Responsiveness to Adenosine 5′-Monophosphate and Exhaled Nitric Oxide Measurements

2003

Objectives To investigate the utility of the determination of airway responsiveness to inhaled adenosine 5′-monophosphate (AMP) and exhaled nitric oxide (ENO) levels as markers for safely reducing the dose of inhaled corticosteroids (ICS) in patients with asthma well controlled with a moderately high ICS dose. Methods A total of 37 patients with asthma well controlled for at least 3 months by treatment with a moderately high ICS dose (beclomethasone dipropionate, 500 to 1,000 μg or equivalent daily) were included in the study. Patients were treated for a 2-week run-in (baseline) period with their usual dose of ICS. For the next 12 weeks, patients were treated with ICS at half the previous d…

Pulmonary and Respiratory MedicineSpirometryInhalationmedicine.diagnostic_testbusiness.industrymedicine.drug_classCritical Care and Intensive Care Medicinemedicine.diseaseBronchodilatorAnesthesiaExhaled nitric oxidemedicineCorticosteroidBronchoconstrictionExpirationmedicine.symptomCardiology and Cardiovascular MedicinebusinessAsthmaChest
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