0000000001131369

AUTHOR

Marcello Guido

showing 3 related works from this author

Efficacy and safety of human papillomavirus vaccination in HIV-infected patients: a systematic review and meta-analysis

2021

AbstractThe prophylactic vaccines available to protect against infections by HPV are well tolerated and highly immunogenic. People with HIV have a higher risk of developing HPV infection and HPV-associated cancers due to a lower immune response, and due to viral interactions. We performed a systematic review of RCTs to assess HPV vaccines efficacy and safety on HIV-infected people compared to placebo or no intervention in terms of seroconversion, infections, neoplasms, adverse events, CD4+ T-cell count and HIV viral load. The vaccine-group showed a seroconversion rate close to 100% for each vaccine and a significantly higher level of antibodies against HPV vaccine types, as compared to the …

0301 basic medicineCD4-Positive T-LymphocytesMaleDisease preventionHIV InfectionsAdolescent Adult Antibodies Viral CD4 Lymphocyte Count CD4-Positive T-Lymphocytes Female HIV Infections Humans Male Papillomavirus Infections Papillomavirus Vaccines Public Health Randomized Controlled Trials as Topic Risk Treatment Outcome Viral Load Virus Shedding Young Adult Patient SafetySettore MED/42 - Igiene Generale E ApplicataAntibodies Viral0302 clinical medicine030212 general & internal medicineViralRandomized Controlled Trials as TopicPublic healthMultidisciplinaryQHPV infectionRViral LoadAdolescent; Adult; Antibodies Viral; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Female; HIV Infections; Humans; Male; Papillomavirus Infections; Papillomavirus Vaccines; Public Health; Randomized Controlled Trials as Topic; Risk; Treatment Outcome; Viral Load; Virus Shedding; Young Adult; Patient SafetyVirus SheddingTreatment OutcomeMedicineFemalePublic HealthPatient SafetyViral loadAdultRiskmedicine.medical_specialtyAdolescentScienceHPV vaccinesPlaceboAntibodiesArticle03 medical and health sciencesPapillomavirus VaccinesYoung AdultInternal medicinemedicineHumansPapillomavirus VaccinesSeroconversionViral sheddingAdverse effectbusiness.industryPapillomavirus InfectionsHealth caremedicine.diseaseCD4 Lymphocyte Count030104 developmental biologybusinessScientific Reports
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Burden and Prevention of HPV. Knowledge, Practices and Attitude Assessment Among Pre-Adolescents and their Parents in Italy

2020

Despite infections due to HPV nowadays represent the most common sexually transmitted diseases worldwide with recognized effective and safe preventive strategies, knowledge, attitudes; however, awareness on HPV is considerably low. The present study has two main objectives: 1. To conduct a literature review to analyze the evolution of preventive tools, the complexity of the vaccine choice process, and the challenges posed by HPV vaccine hesitancy and refusal among pre-adolescents and their parents; 2. To assess knowledge, practices and attitudes toward HPV infection and vaccination in a sample of Italian pre-adolescents and their parents. The observational study was carried out through the…

AdultMaleParentsHealth Knowledge Attitudes Practicemedicine.medical_specialtyHPVknowledgePre adolescentsTarget populationAdolescentsArticle03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesIntervention (counseling)Drug DiscoverymedicineHumansPapillomavirus VaccinesAdolescents; Attitude; HPV; Knowledge; Parents; Practice; Vaccine030212 general & internal medicineChildAgedPharmacologybusiness.industryPapillomavirus InfectionsVaccinationHPV infectionMiddle AgedPatient Acceptance of Health Caremedicine.diseasepracticevaccine.VaccinationparentCross-Sectional StudiesItaly030220 oncology & carcinogenesisFamily medicineadolescentattitudeFemaleHealth educationObservational studybusinessVaccineHpv knowledge
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The impact of ten years of infant universal Varicella vaccination in Sicily, Italy (2003-2012).

2015

Introduction Universal varicella vaccination in Sicily was introduced in infant population since 2003, with a rapidly increasing coverage. Aim of the present study was to analyze changes in the epidemiology of varicella since the introduction of universal vaccination. Methods The study was performed by analyzing Sicilian administrative/clinical data on varicella case notifications and hospitalizations from 2003 to 2012 (ICD-9-CM discharge diagnosis codes 052 and 052.×). MMR+V and V coverage were also calculated for each birth cohort. Moreover, blood samples drawn in 2013/2014 from general population stratified by age were tested for varicella antibodies. Results From 2003 to 2012, 15 433 va…

AdultMalePediatricsmedicine.medical_specialtyAdolescentImmunologyPopulationSocio-culturalecoverageVaricella vaccinationAntibodies ViralSettore MED/42 - Igiene Generale E ApplicataChickenpox VaccineYoung AdultChickenpoxvaricellaEpidemiologyHumansImmunology and AllergyMedicineYoung adultChildeducationDisease NotificationSicilyChickenpox VaccineHospitalizationsPharmacologyeducation.field_of_studyChickenpoxbusiness.industryVaccinationInfant NewbornInfantNotificationsmedicine.diseaseHospitalizationVaccinationCoverage; Epidemiology; Hospitalizations; Notifications; Sicily; Universal mass vaccination; VaricellaChild PreschoolFemaleepidemiologynotificationbusinessBirth cohortuniversal mass vaccinationHumanResearch Paperhospitalization
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