Cigarette smoke upregulates TLR4 expression and enhances TLR4 mediated responses

Obstructive sleep apnea does not affect circulating hematopoietic precursors

Tumori polmonari

L’analisi dei microsatelliti nel condensato aereo polmonare di pazienti con patologie tumorali polmonari come nuova metodologia per la diagnosi precoce.

L’asma bronchiale

Malattie dell'Apparato Respiratorio

Fisiopatologia respiratoria

Elevated expression of prostaglandin receptor and increased release of prostaglandin E maintain the survival of CD45RO T cells in the inflamed human pleural space.

Generalità anatomofunzionali

Altered expression of TLR4 and beta 2 defensin in chronic obstructive pulmonary disease

Hypoallergenic fragment of Parj 2 increases functional expression of toll like receptor in atopic children

Circulating CD34+ cells are decreased in chronic obstructive pulmonary disease (COPD).

Semeiotica clinica dell'apparato respiratorio

Cigarette smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses

DOES LEPTIN PLAY A CYTOKINE ROLE WITHIN THE AIRWAYS OF COPD PATIENTS?

THE M3 MUSCARINIC RECEPTOR IS INVOLVED IN THE ACTIVATION OF AIRWAY EPITHELIUM IN VITRO

Semeiotica funzionale

Effetti delle variazioni climatiche sulle cellule delll'espettorato indotto in maratoneti amatoriali

Longitudinal assessment of TGFb, MMP-9 and TIMP-1 in induced sputum of children with intermittent and moderate asthma.

Malformaioni polmonari

Sindrome da sofferenza respiratoria acuta (ARDS).

Cigarette smoke increases TLR4 expression and modifies LPS mediated responses in airway epithelial cells.

Pleural mesothelial cells express both BLT2 and PPARa and mount an integrated response to pleural LTB4

Embriologia, sviluppo e invecchiamento dell'apparato respiratorio

Apoptosis in induced sputum cells in long-distance runners: a longitudinal study.

Multiple synergystic effects of fluticasone propionate and salmeterol on T lymphocyte activation in asthma

Tubercolosi polmonare

Bronchiectasie

Role of PGE2 in the invasiveness, growth and protection of cancer cells in malignant pleuritis

Abstract The recurrence of pleural effusions is a common event in a variety of neoplastic diseases. The objective of this study was to identify the mechanisms promoting the homing and growth of cancer cells within the pleural space. A cancer cell line recovered from malignant pleural fluids (lung adenocarcinoma cell line) that constitutively expresses cyclooxygenase 2 (COX-2) and all types of prostaglandin receptors was studied. It was first demonstrated using a matrigel system, that malignant pleural fluids increase the invasiveness of adenocarcinoma cells more than congestive heart failure (CHF) pleural fluids. Moreover, exposure to exudative malignant, but not to CHF pleural fluids, incr…

Pleural LTB4 upregulates ICAM-1 molecules via STAT-1 activation on pleural mesothelial cells

The release of PGE2 by pleural macrophage prolongs the survival of T lymphocytee within the inflamed human pleural space

Riduzione dei CD34+ circolanti nella broncopneumopatia cronica ostruttiva (BPCO)

Partecipazione polmonare nella sindrome da immunodeficienza acquisita (AIDS)

Increased airway inflammatory cells in endurance athletes: what do they mean?

Inflammatory cells are increased in the airways of endurance athletes, but their role in causing exercise-induced respiratory symptoms and bronchoconstriction, or their possible long-term consequences, are uncertain.To put the results of athlete studies in perspective, by analysing the pathogenesis of airway cell changes and their impact on respiratory function.Athletes of different endurance sports at rest showed increased airway neutrophils. Elite swimmers and skiers also showed large increases in airway eosinophils and lymphocytes, possibly related to chronic, exercise-related exposure to irritants or cold and dry air, respectively. Post-exercise studies reported variable responses of ai…

Functional role of PAR-1 receptors in the epithelial cells of smokers with and without COPD: involvement of intracellular pathway

The expression of muscarinic receptors is involved in the p42/44 ERK and NF-KB activation of human lung fibroblasts from COPD subjects

Effects of acute CPAP application on baroreflex control of heart rate during sleep in severe obstructive sleep apnea.

Baroreflex control of heart rate during sleep (baroreflex sensitivity; BRS) has been shown to be depressed in obstructive sleep apnoea (OSA), and improved after treatment with continuous positive airway pressure (CPAP). Whether CPAP also acutely affects BRS during sleep in uncomplicated severe OSA is still debatable. Blood pressure was monitored during nocturnal polysomnography in 18 patients at baseline and during first-time CPAP application. Spontaneous BRS was analysed by the sequence method, and estimated as the mean sequence slope. CPAP did not acutely affect mean blood pressure or heart rate but decreased cardiovascular variability during sleep. Mean BRS increased slightly during CPAP…

Asma bronchiale

Endurance training increases infiammatori cells in small airways of mice.