0000000001133425
AUTHOR
Boris Federico Abbate
Nuovi gel di Fricke ad alta sensibilità e bassa diffusione per dosimetria 3D tramite MRI
One of the most recent and promising developments in radiotherapy dosimetry was the introduction of 3D radiationsensitive gels. These gels present tissue equivalent composition and density, so they also serve as phantoms, and their response is largely independent of radiation quality and dose rate. Some gels are infused with ferrous sulfate and rely on the radiation-induced oxidation of ferrous ions to ferric ions (Fricke-gel). In this work Fricke gel dosimeters produced with a matrix of poly-vinyl alcohol (PVA) cross-linked with glutaraldehyde (GTA) were analyzed with magnetic resonance imaging (MRI). This work focused on the analysis of the temporal diffusion of ferric ions through PVA-GT…
Analysis of response of PVA-GTA Fricke gel dosimeters through magnetic resonance imaging.
The experimental activities here reported are focused on the analysis of the clinical applications of Fricke gel dosimeters produced with a matrix of Polyvinyl alcohol (PVA) cross-linked by adding glutaraldehyde (GTA). The analyses were performed by means of a 1.5 T clinical magnetic resonance imaging (MRI) scanner. The sensitivity of these dosimetric gels to clinical photon beams as well as the signal stability were suitably investigated. Furthermore, the effect of the xylenol orange on the MRI signal was analyzed. The results obtained show that these PVA-GTA gel dosimeters show good dosimetric features for possible future use for 3D dose mapping in clinical applications.