0000000001134803

AUTHOR

Prisco Domenico

showing 6 related works from this author

Impact of Diabetes Mellitus and Its Comorbidities on Elderly Patients Hospitalized in Internal Medicine Wards: Data from the RePoSi Registry

2022

Background: Currently, diabetes represents the seventh leading cause of death worldwide, with a significant economic burden. The number and severity of comorbidities increase with age, and are identified as important determinants that influence the prognosis. We aimed to investigate comorbidities and outcomes in a cohort of hospitalized elderly patients affected by diabetes. Methods: In this observational study, we retrospectively analyzed data collected from the REgistro dei pazienti per lo studio delle POlipatologie e politerapie in reparti della rete Simi (RePoSi) registry. Socio-demographic, clinical characteristics, and laboratory findings were considered. The association between varia…

Leadership and Management1-year mortality cancer comorbidities diabetes heart rate in-hospital mortality male sex.Heart rateSocio-culturaleHealth InformaticscomorbiditiesArticleComorbiditiesHealth Information Managementdiabetes; comorbidities; heart rate; cancer; male sex; in-hospital mortality; 1-year mortalityheart ratecancer1-year mortality; Cancer; Comorbidities; Diabetes; Heart rate; In-hospital mortality; Male sexLS4_4Cancerdiabetesmale sexHealth PolicyDiabetesRMale sexIn-hospital mortality1-year mortalityMedicine1-year mortality Cancer Comorbidities Diabetes Heart rate In-hospital mortality Malein-hospital mortality
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Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoS…

2021

Abstract Aims The association between hyperglycemia at hospital admission and relevant short- and long-term outcomes in elderly population is known. We assessed the effects on mortality of hyperglycemia, disability, and multimorbidity at admission in internal medicine ward in patients aged ≥ 65 years. Methods Data were collected from an active register of 102 internal medicine and geriatric wards in Italy (RePoSi project). Patients were recruited during four index weeks of a year. Socio-demographic data, reason for hospitalization, diagnoses, treatment, severity and comorbidity indexes (Cumulative Illness rating Scale CIRS-SI and CIRS-CI), renal function, functional (Barthel Index), and cog…

RegistrieMaleComorbidity; Diabetes; Disability; Elderly; Hyperglycemia; Mortality; Aged; Aged 80 and over; Comorbidity; Female; Hospital Mortality; Hospitals; Humans; Internal Medicine; Male; Registries; Hospitalization; Hyperglycemiamedicine.medical_specialtyEndocrinology Diabetes and MetabolismSocio-culturaleRenal functionComorbidity; Diabetes; Disability; Elderly; Hyperglycemia; MortalityComorbidity030204 cardiovascular system & hematologyDiabeteHospital03 medical and health sciences0302 clinical medicineEndocrinologyElderlyRating scaleInternal medicineDiabetes mellitus80 and overInternal MedicinemedicineHumansLS4_4Hospital MortalityRegistries030212 general & internal medicineMortalityAgedAged 80 and overDisabilityClass III obesitybusiness.industryMortality rateDiabetesComorbidity Diabetes Disability Elderly Hyperglycemia MortalityGeneral Medicinemedicine.diseaseComorbidityHospitalsHospitalizationMood disordersHyperglycemiaMortality.FemaleGeriatric Depression ScaleOriginal ArticlebusinessHumanActa Diabetologica
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Pain and Frailty in Hospitalized Older Adults

2020

Introduction Pain and frailty are prevalent conditions in the older population. Many chronic diseases are likely involved in their origin, and both have a negative impact on quality of life. However, few studies have analysed their association. Methods In light of this knowledge gap, 3577 acutely hospitalized patients 65 years or older enrolled in the REPOSI register, an Italian network of internal medicine and geriatric hospital wards, were assessed to calculate the frailty index (FI). The impact of pain and some of its characteristics on the degree of frailty was evaluated using an ordinal logistic regression model after adjusting for age and gender. Results The prevalence of pain was 24.…

medicine.medical_specialtyPain medicineSocio-culturaleChronic painOsteoarthritisAffect (psychology)Chronic pain; Internal medicine and geriatric wards; Musculoskeletal diseasesOlder populationChronic pain Internal medicine and geriatric wards Musculoskeletal diseasesQuality of lifeMusculoskeletal diseaseInternal medicine and geriatric wardsAnesthesiologyInternal medicinemedicineRD78.3-87.3LS4_4Original Researchbusiness.industryMusculoskeletal diseasesChronic painmedicine.diseaseInternal medicine and geriatric wardMusculoskeletal diseases.Anesthesiology and Pain MedicineRheumatoid arthritisNeurology (clinical)Ordered logitbusiness
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Clinical Severity, Age, and Sex Overcome Cardiometabolic Morbidities but Not Stroke as Predictors of Mortality in Elderly Inpatients: Data From the R…

2016

MalePediatricsmedicine.medical_specialtyREPOSI studyClinical severity age stroke risk factors elderly REPOSI studySocio-culturale030204 cardiovascular system & hematologyAge and sexelderlySeverity of Illness Index03 medical and health sciencesSex Factors0302 clinical medicineMetabolic Diseasesmedicinerisk factorsHumansClinical severityClinical severityHospital MortalityRegistries030212 general & internal medicineStrokeAgedAged 80 and overInpatientsbusiness.industryAge Factorsmedicine.diseaseStrokeageItalyCardiovascular DiseasesFemaleMorbidityGeriatrics and GerontologybusinessJournal of the American Geriatrics Society
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Antipsychotic prescription and mortality in hospitalized older persons

2016

Background: Recent scientific reports have shown that older persons treated with antipsychotics for dementia-related behavioural symptoms have increased mortality. However, the impact of these drugs prescribed during hospitalization has rarely been assessed. We aimed to investigate whether antipsychotics are associated with an increased risk of mortality during hospitalization and at 3-month follow-up in elderly inpatients. Methods: We analyzed data gathered during two waves (2010 and 2012) by the REPOSI (Registro Politerapie Società Italiana Medicina Interna). All new prescriptions of antipsychotic drugs during hospitalization, whether maintained or discontinued at discharge, were collect…

MaleSocio-culturaleOlder personAntipsychoticCognitionEconomicaAntipsychotics; Hospitalization; Mortality; Older persons; Gerontology; Geriatrics and Gerontology; Psychiatry and Mental HealthHumansMortalityPsychomotor AgitationAgedantipsychotics hospitalization mortality older personsAged 80 and overMental DisordersPatient DischargeHospitalizationantipsychoticsItalyantipsychotics; hospitalization; mortality; older personsPsychiatry and Mental Healtholder personsDementiaFemaleGeriatrics and GerontologyGerontologyAntipsychotic Agents
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Kidney Disease Management in the Hospital Setting: A Focus on Inappropriate Drug Prescriptions in Older Patients

2021

Aging with multimorbidity and polytherapy are the most significant factors that could led to inappropriate prescribing of contraindicated medications in patients with chronic kidney disease (CKD). The aim of this study was to evaluate the prescriptions of contraindicated drugs in older adults in CKD and to identify their associated factors in a hospital context. An observational retrospective study was carried out considering all patients ≥65 years with at least one serum creatinine value recorded into the REPOSI register into 2010–2016 period. The estimated glomerular filtration rate (eGFR) was applied to identify CKD. A descriptive analysis was performed to compare demographic and clinica…

medicine.medical_specialtyappropriateness of prescriptionprescribing patternsRenal functionContext (language use)RM1-950Logistic regressionNOchemistry.chemical_compoundolder patientInternal medicinehospital settingmedicinePharmacology (medical)LS4_4Medical prescriptionprescribing patternappropriateness of prescriptions chronic kidney disease hospital setting older patients prescribing patterns real-world data.Original ResearchPharmacologyCreatininereal-world databusiness.industryRetrospective cohort studymedicine.diseaseolder patientsreal-world data.appropriateness of prescriptions; chronic kidney disease; hospital setting; older patients; prescribing patterns; real-world dataappropriateness of prescriptionschemistryObservational studyTherapeutics. Pharmacologybusinesschronic kidney diseaseKidney diseaseFrontiers in Pharmacology
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