6533b7dafe1ef96bd126f645

RESEARCH PRODUCT

Pain and Frailty in Hospitalized Older Adults

Ilaria ArdoinoCarlotta FranchiAlessandro NobiliPier Mannuccio MannucciOscar Corli Pier Mannuccio MannucciNobili AlessandroPietrangelo AntonelloPerticone FrancescoLicata GiuseppeVioli Francesco Gino Roberto CorazzaCorrao SalvatoreMarengoni AlessandraSalerno FrancescoCesari MatteoTettamanti MauroPasina LucaFranchi CarlottaFranchi CarlottaCortesi LauraTettamanti MauroMiglio GabriellaTettamanti MauroCortesi LauraArdoino IlariaNovella AlessioPrisco DomenicoSilvestri ElenaEmmi GiacomoBettiol AlessandraMattioli IreneBiolo GianniZanetti MichelaBartelloni GiacomoVanoli MassimoGrignani Giulia Edoardo Alessandro PulixiLupattelli GrazianaBianconi VanessaAlcidi RiccardoGirelli DomenicoBusti FabianaMarchi GiacomoBarbagallo MarioDominguez LigiaBeneduce VincenzaCacioppo FedericaCorrao SalvatoreNatoli GiuseppeMularo SalvatoreRaspanti MassimoZoli Marco Maria Laura MatacenaOrio GiuseppeMagnolfi EleonoraSerafini GiovanniSimili AngeloPalasciano Giuseppe Maria Ester Modeo Carla Di Gennaro Maria Domenica CappelliniFabio Giovanna Margherita Migone De Amicis Giacomo De LucaScaramellini NataliaCesari Matteo Paolo Dionigi RossiDamanti SarahClerici MartaLeoni Simona Alessandra Danuta Di Mauro Antonio Di SabatinoMiceli Emanuela Marco Vincenzo LentiPisati Martina Costanza Caccia DominioniPontremoli RobertoBeccati ValentinaNobili GiuliaLeoncini GiovannaAnastasio LuigiCarbone MariaCipollone Francesco Maria Teresa GuagnanoRossi IlariaMancuso GerardoCalipari DanielaBartone MosèDelitala GiuseppeBerria MariaDelitala AlessandroMuscaritoli MaurizioMolfino AlessioPetrillo EnricoGiorgi AntonellaGracin ChristianZuccalà GiuseppeD'aurizio GabriellaRomanelli GiuseppeMarengoni AlessandraVolpini AndreaLucente DanielaPicardi Antonio Umberto Vespasiani GentilucciGallo PaoloBellelli GiuseppeCorsi MaurizioAntonucci CesareSidoli ChiaraPrincipato GiuliaArturi FrancoSuccurro ElenaTassone BrunoGiofrè Federica Maria Grazia Serra Maria Antonietta BleveBrucato Antonio Teresa De FalcoFabris FabrizioBertozzi IreneBogoni Giulia Maria Victoria RabuiniPrandini TancrediManfredini RobertoFabbian FabioBoari Benedetta Alfredo De GiorgiTiseo RuanaPaolisso Giuseppe Maria Rosaria RizzoCatalano ClaudiaBorghi ClaudioStrocchi EnricoIanniello EugeniaSoldati MarioSchiavone SilviaBragagni AlessioSabbà Carlo Francesco Saverio VellaSuppressa Patrizia Giovanni Michele De VincenzoComitangelo AlessioAmoruso EmanueleCustodero CarloFenoglio LuigiFalcetta AndreaL Fracanzani AnnaTiraboschi SilviaCespiati AnnalisaOberti GiovannaSigon GiordanoPeyvandi FloraRossio RaffaellaColombo GiuliaAgosti PasqualeMonzani ValterSavojardo ValeriaCeriani GiulianaSalerno FrancescoPallini GiadaFabrizio MontecuccoOttonello LucianoCaserza LaraVischi Giulia Nicola Lucio LiberatoTognin TizianaPurrello Francesco Antonino Di PinoPiro SalvatoreRozzini RenzoFalanga Lina Maria Stella Pisciotta Francesco Baffa BellucciBuffelli StefanoMontrucchio GiuseppePeasso PaoloFavale EdoardoPoletto CesareMargaria CarlSanino MauraVioli FrancescoPerri LudovicaGuasti LuiginaCastiglioni LuanaMaresca AndreaSquizzato AlessandroCampiotti LeonardoGrossi Alessandra Roberto Davide DiprizioBertolotti MarcoMussi ChiaraLancellotti Giulia Maria Vittoria LibbraGalassi MatteoGrassi YasmineGreco AlessioSciacqua AngelaPerticone MariaBattaglia RosaMaio RaffaeleStanghellini VincenzoRuggeri Eugenio Sara Del VecchioSalvi AndreaLeonardi RobertoDamiani GiampaoloCapeci WilliamMattioli Massimo Giuseppe Pio MartinoBiondi LorenzoPettinari PietroGhio Riccardo Anna Dal ColMinisola SalvatoreColangelo LucianoCilli MirellaLabbadia GiancarloAfeltra AntonellaMarigliano Benedetta Maria Elena PipitaCastellino PietroZanoli LucaGennaro AlfioGaudio AgostinoSaracco ValterFogliati MarisaBussolino CarloMete FrancescaGino MiriamVigorito CarloCittadini AntonioMoreo GuidoProlo SilviaPina GloriaBallestrero AlbertoFerrando FabioRoberta GonellaCerminara DomenicoBerra SergioDassi Simonetta Maria Cristina NavaGraziella BrunoBaldassarre StefanoFragapani SalvatoreGruden GabriellaGalanti GiorgioMascherini GabrielePetri CristianStefani LauraGirino MargheritaPiccinelli ValeriaNasso FrancescoGioffrè VincenzaPasquale MariaSechi LeonardoCatena CristianaColussi GianlucaCavarape Alessandro Andea Da PortoPassariello NicolaRinaldi LucaBerti FrancoFamularo GiuseppeTarsitani PatriziaCastello RobertoPasino Michela Gian Paolo Ceda Marcello Giuseppe MaggioMorganti SimonettaArtoni AndreaGrossi Margherita Stefano Del GiaccoFirinu DavideCostanzo GiuliaArgiolas GiacomoMontalto GiuseppeLicata Anna Filippo Alessandro MontaltoCorica FrancescoBasile GiorgioCatalano AntoninoBellone FedericaPrincipato ConcettoMalatino LorenzoStancanelli BenedettaTerranova Valentina Salvatore Di Marca Rosario Di Quattro Lara La MalfaCaruso RossellaMecocci PatriziaRuggiero CarmelindaBoccardi VirginiaMeschi TizianaTicinesi AndreaNouvenne AntonioMinuz PietroFondrieschi Luigi Giandomenico Nigro ImperialePirisi Mario Gian Paolo FraSola DanieleBellan MattiaPorta MassimoRiva PieroQuadri RobertoLarovere EricaNovelli MarcoScanzi GiorgioMengoli CaterinaProvini StellaRicevuti LauraSimeone EmilioScurti RosaTolloso FabioTarquini RobertoValoriani AliceDolenti SilviaVannini GiuliaVolpi RiccardoBocchi PietroVignali AlessandroHarari SergioLonati ChiaraNapoli FedericoAiello ItaliaLandolfi RaffaeleMontalto MassimoMirijello AntonioPurrello Francesco Antonino Di PinoE Cognome Del Primario NomeGhidoni SilviaSalvatore TeresaMonaco LucioRicozzi CarmenPilotto AlbertoIndiano IlariaGandolfo FedericaInvestigator Reposi

subject

medicine.medical_specialtyPain medicineSocio-culturaleChronic painOsteoarthritisAffect (psychology)Chronic pain; Internal medicine and geriatric wards; Musculoskeletal diseasesOlder populationChronic pain Internal medicine and geriatric wards Musculoskeletal diseasesQuality of lifeMusculoskeletal diseaseInternal medicine and geriatric wardsAnesthesiologyInternal medicinemedicineRD78.3-87.3LS4_4Original Researchbusiness.industryMusculoskeletal diseasesChronic painmedicine.diseaseInternal medicine and geriatric wardMusculoskeletal diseases.Anesthesiology and Pain MedicineRheumatoid arthritisNeurology (clinical)Ordered logitbusiness

description

Introduction Pain and frailty are prevalent conditions in the older population. Many chronic diseases are likely involved in their origin, and both have a negative impact on quality of life. However, few studies have analysed their association. Methods In light of this knowledge gap, 3577 acutely hospitalized patients 65 years or older enrolled in the REPOSI register, an Italian network of internal medicine and geriatric hospital wards, were assessed to calculate the frailty index (FI). The impact of pain and some of its characteristics on the degree of frailty was evaluated using an ordinal logistic regression model after adjusting for age and gender. Results The prevalence of pain was 24.7%, and among patients with pain, 42.9% was regarded as chronic pain. Chronic pain was associated with severe frailty (OR = 1.69, 95% CI 1.38–2.07). Somatic pain (OR = 1.59, 95% CI 1.23–2.07) and widespread pain (OR = 1.60, 95% CI 0.93–2.78) were associated with frailty. Osteoarthritis was the most common cause of chronic pain, diagnosed in 157 patients (33.5%). Polymyalgia, rheumatoid arthritis and other musculoskeletal diseases causing chronic pain were associated with a lower degree of frailty than osteoarthritis (OR = 0.49, 95%CI 0.28–0.85). Conclusions Chronic and somatic pain negatively affect the degree of frailty. The duration and type of pain, as well as the underlying diseases associated with chronic pain, should be evaluated to improve the hospital management of frail older people. Electronic Supplementary Material The online version of this article (10.1007/s40122-020-00202-3) contains supplementary material, which is available to authorized users.

yearjournalcountryeditionlanguage
2020-10-15
10.1007/s40122-020-00202-3http://hdl.handle.net/11392/2425589