0000000001135766

AUTHOR

Javier Fernandez-de-simon

0000-0002-2756-758x

showing 2 related works from this author

Seasonal diet-based resistance to anticoagulant rodenticides in the fossorial water vole (Arvicola amphibius)

2021

International audience; Anticoagulant rodenticides (AR) resistance has been defined as "a major loss of efficacy due to the presence of a strain of rodent with a heritable and commensurately reduced sensitivity to the anticoagulant". The mechanism that supports this resistance has been identified as based on mutations in the Vkorc1 gene leading to severe resistance in rats and mice. This study evaluates the validity of this definition in the fossorial water vole and explores the possibility of a non-genetic diet-based resistance in a strict herbivorous rodent species. Genetic support was explored by sequencing the Vkorc1 gene and the diet-based resistance was explored by the dosing of vitam…

Diet-based resistanceVitaminVitamin KRodentZoology[SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chain010501 environmental sciences01 natural sciencesBiochemistryMice03 medical and health scienceschemistry.chemical_compound0302 clinical medicineVitamin K Epoxide Reductasesbiology.animalAnimals030212 general & internal medicine[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Water voleAllele frequency0105 earth and related environmental sciencesGeneral Environmental Science2. Zero hungerHerbivore[SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal HealthbiologyResistance (ecology)ArvicolinaeFossorialAnticoagulantsMembrane ProteinsRodenticidesbiology.organism_classificationDietRatsAnticoagulant rodenticidesVKORC1chemistryArvicolaSeasons[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/EcotoxicologyWater vole[SDV.AEN]Life Sciences [q-bio]/Food and NutritionEnvironmental Research
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Trophic transfer of pesticides: The fine line between predator–prey regulation and pesticide–pest regulation

2020

International audience; Understanding pesticide impacts on populations of target/non-target species and communities is a challenge to applied ecology. When predators that otherwise regulate pest densities ingest prey contaminated with pesticides, this can suppress predator populations by secondary poisoning. It is, however, unknown how species relationships and protocols of treatments (e.g. anticoagulant rodenticide [AR]) interact to affect pest regulation.To tackle this issue, we modelled a heuristic non-spatialized system including montane water voles, specialist vole predators (stoats, weasels) and a generalist predator (red fox) which consumes voles, mustelids and other prey. By carryin…

0106 biological sciencesPopulation010603 evolutionary biology01 natural sciencesPredationsensitivity analysisSecondary poisoningecological controlEcosystemeducationPredatorTrophic level2. Zero hungereducation.field_of_studyEcologybiologyEcology010604 marine biology & hydrobiologypesticides15. Life on landPesticidebiology.organism_classificationcyclic fluctuationssecondary poisoningecosystem service13. Climate actionVolebiodiversity conservation[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicologycascade effectsJournal of Applied Ecology
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