0000000001136569
AUTHOR
Francesco Barbaro
Profiling the risk of hepatocellular carcinoma after long-term HCV eradication in patients with liver cirrhosis in the PITER cohort
Background and aims: Severe liver disease markers assessed before HCV eradication are acknowledged to usually improve after the SVR. We prospectively evaluated, in the PITER cohort, the long-term HCC risk profile based on predictors monitored after HCV eradication by direct-acting antivirals in patients with cirrhosis. Methods: HCC occurrence was evaluated by Kaplan-Meier analysis. Cox regression analysis identified the post-treatment variables associated with de-novo HCC; their predictive power was presented in a nomogram. Results: After the end of therapy (median follow-up:28.47 months), among 2064 SVR patients, 119 (5.8%) developed de-novo HCC. The HCC incidence was 1.90%, 4.21%, 6.47% a…
Clinical features and comorbidity pattern of HCV infected migrants compared to native patients in care in Italy: A real-life evaluation of the PITER cohort
Background: Direct-acting antivirals are highly effective for the treatment of hepatitis C virus (HCV) infection, regardless race/ethnicity. We aimed to evaluate demographic, virological and clinical data of HCV-infected migrants vs. natives consecutively enrolled in the PITER cohort. Methods: Migrants were defined by country of birth and nationality that was different from Italy. Mann-Whitney U test, Chi-squared test and multiple logistic regression were used. Results: Of 10,669 enrolled patients, 301 (2.8%) were migrants: median age 47 vs. 62 years, (p < 0.001), females 56.5% vs. 45.3%, (p < 0.001), HBsAg positivity 3.8% vs. 1.4%, (p < 0.05). Genotype 1b was prevalent in both gro…
De re uxoria
Ms. il·luminat Títol obtingut de full de guarda am lletra de la segona meitat del segle XV. El mateix text amb una escritura del segle XVII Col·lació: Vitel·la, f. i (pergamí actual) + 78 + i (pergamí actual) ; foliació moderna a llapis ; reclams verticals cada vuit fulls Composició: Escrit a línia tirada a 22 línies Escriptura: Humanística antiqua. Copiat per Giovan Marco Cinico (f. 78r) Decoració: Orla i inicials adornades, escut (tipus 10) De Marinis, belles caplletres miniades en or i colors; el recte dels fulls 3 i 7 i algunes línies en or; els títols i notes marginals en vermell, violeta i verd; en el frontispici escut dels monarques de Nàpols sostingut per dos àngels. Miniatures atri…