0000000001139018

AUTHOR

Miriam Rossi

0000-0001-9609-474x

showing 3 related works from this author

Protection by extra virgin olive oil against oxidative stress in vitro and in vivo. Chemical and biological studies on the health benefits due to a m…

2017

Abstract We report the results of in vivo studies in Caenorhabditis elegans nematodes in which addition of extra virgin olive oil (EVOO) to their diet significantly increased their life span with respect to the control group. Furthermore, when nematodes were exposed to the pesticide paraquat, they started to die after two days, but after the addition of EVOO to their diet, both survival percentage and lifespans of paraquat-exposed nematodes increased. Since paraquat is associated with superoxide radical production, a test for scavenging this radical was performed using cyclovoltammetry and the EVOO efficiently scavenged the superoxide. Thus, a linear correlation (y = -0.0838x +19.73, regres…

Animals; Caenorhabditis elegans; Cell Cycle; Cell Line; Electron Spin Resonance Spectroscopy; Humans; In Vitro Techniques; Olive Oil; Oxidative Stress; Paraquat; Rats; Reactive Oxygen Species; Diet Mediterranean0301 basic medicineAntioxidantmedicine.medical_treatmentlcsh:MedicineMediterraneanmedicine.disease_causeDiet MediterraneanBiochemistryAntioxidantsMonocytesMyoblastschemistry.chemical_compoundWhite Blood Cells0302 clinical medicineParaquatGalvinoxylSuperoxidesAnimal CellsPlant ProductsMedicine and Health SciencesElectrochemistryFood sciencelcsh:Sciencechemistry.chemical_classificationMultidisciplinarySuperoxideStem CellsCell CycleAgricultureOxidesLipidsPeroxidesHydroperoxideChemistry030220 oncology & carcinogenesisPhysical SciencesCellular TypesResearch ArticleParaquatImmune CellsImmunologyIn Vitro TechniquesSettore BIO/09Vegetable OilsCell Line03 medical and health sciencesmedicineAnimalsHumansSettore BIO/10Caenorhabditis elegansOlive OilReactive oxygen speciesBlood CellsElectrode Potentialslcsh:RElectron Spin Resonance SpectroscopyChemical CompoundsBiology and Life SciencesCell BiologyAgronomyDietRatsTyrosolOxidative Stress030104 developmental biologychemistryHydroxytyrosollcsh:QReactive Oxygen SpeciesOilsOxidative stressCrop Science
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5-Amino-1-phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid

2009

In the title compound, C11H8F3N3O2, there are two molecules in the asymmetric unit wherein the phenyl rings make dihedral angles of 65.3 (2) and 85.6 (2)° with the pyrazole rings. In the crystal, pairs of molecules are held together by O—H...O hydrogen bonds between the carboxyl groups, forming a centrosymmetric dimer with an R22(8) motif. Intramolecular N—H...O interactions are also present.

chemistry.chemical_classificationHydrogen bondDimerCarboxylic acidGeneral ChemistryPyrazoleDihedral angle010402 general chemistry010403 inorganic & nuclear chemistryCondensed Matter PhysicsBioinformaticsOrganic Papers01 natural sciencesMedicinal chemistry3. Good health0104 chemical sciencesCrystallcsh:Chemistrychemistry.chemical_compoundchemistrylcsh:QD1-999X-ray studyGeneral Materials ScienceActa Crystallographica Section E
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Tin( II ) and Lead( II ) 4‐Acyl‐5‐pyrazolonates: Synthesis, Spectroscopic and X‐ray Structural Characterization

2004

Novel tin(II) β-diketonate Sn(Q)2 complexes [HQ = 1-R1-3-R3-4-R4(C=O)-pyrazol-5-one; HQC: R1 = Ph, R3 = Me, R4 = Cy; HQS: R1 = Ph, R3 = Me, R4 = CHPh2; HQL: R1 = Ph, R3 = Me, R4 = CH2Ph; HQT: R1 = Ph, R3 = Me, R4 = CH2tBu; HQE: R1 = Ph, R3 = Me, R4 = Et; HQB: R1 = Ph, R3 = Me, R4 = tBu; HQW: R1 = Ph, R3 = Me, R4 = p-(tBu)Ph; HQR: R1 = Ph, R3 = Me, R4 = p-[(CH2)5CH3]Ph; HQN: R1 = p-NO2Ph, R3 = Me, R4 = Ph; HQM: R1 = Me, R3 = Me, R4 = Ph; HQD: R1 = Me, R3 = Me, R4 = Me; HQP: R1 = Ph, R3 = Ph, R4 = Ph; HQG: R1 = Ph, R3 = Ph, R4 = Me; HQF: R1 = p-CF3Ph, R3 = Me, R4 = Ph; HQH: R1 = p-CF3Ph, R3 = Me, R4 = Me] have been isolated and characterized by single-crystal X-ray diffraction analyses, IR, 1…

Steric effectsStereochemistryChemistryCoordination numberCrystal structureNuclear magnetic resonance spectroscopyInorganic ChemistryMetalCrystallographyMolecular geometryCovalent radiusvisual_artvisual_art.visual_art_mediumReactivity (chemistry)European Journal of Inorganic Chemistry
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